EGFR, Soluble (human) (rec.)

EGFR, Soluble (human) (rec.)
%
Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
AG-40T-0041-C025 25 µg -

3 - 9 business days*

10 %
600.00€
540.00€
 
Human EGFR (629aa) is fused at the C-terminus to a Strep-tag. Lyophilized. EGFR has been shown to... more
Product information "EGFR, Soluble (human) (rec.)"
Human EGFR (629aa) is fused at the C-terminus to a Strep-tag. Lyophilized. EGFR has been shown to bind a subset of the EGF family ligands, including EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, heparin-binding EGF and neuregulin-2 in the absence of a co-receptor. Ligand binding induces EGFR homodimerization as well as heterodimerization with ErbB2, resulting in kinase activation, tyrosine phosphorylation and cell signaling. EGFR signaling has been shown to regulate multiple biological functions including cell proliferation, differentiation, motility and apoptosis. In addition, EGFR signaling has also been shown to play a role in carcinogenesis.
Keywords: EGFR, ERBB, EC=2.7.10.1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, Receptor tyrosine-protein kinase erbB-1
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-40T-0041

Properties

Application: Bioassay
Conjugate: No
Host: Insect cells
Species reactivity: human
MW: 85 kD
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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