5 products were found matching "Cay10628-25"!
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EED (human recombinant)
Item number: Cay10628-50
The human-Embryonic ectoderm development (EED) protein is a WD40 repeat-containing protein that forms part of the Polycomb repressive complex 2 (PRC2). The PRC2 core complex contains the catalytic subunit EZH2 (Enhancer of zeste 2), SUZ12 (Suppressor of zeste) and EED. The EED subunit does not contain...
| Keywords: | hEED, hEED, WAIT-1, WAIT-1, Polycomb protein EED {ECO:0000305}, Polycomb protein EED {ECO:0000305}, WD protein associating... |
| Application: | WB |
| MW: | 53,5 kD |
473.00€
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JWH 145
Item number: Cay10825-25
Several aminoalkylindole cannabinoids (CB), including JWH 018 and JWH 073, have been detected in herbal blends. JWH 145 (Cay-10825) is a (1-naphthoyl)pyrrole analog of JWH 018 that potently activates both CB1 and CB2 receptors (Ki values of 14 and 6.4 nM, respectively). Its biological properties have not been...
| Keywords: | 1-naphthalenyl(1-pentyl-5-phenyl-1H-pyrrol-3-yl)-methanone |
| Application: | Analytical reference standard, synthetic cannabinoid, (1-naphthoyl)pyrrole JWH 018 analog |
| CAS | 914458-19-8 |
| MW: | 367.5 D |
From 241.00€
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PLX4032
Item number: Cay10618-25
PLX4032 is an orally bioavailable, ATP-competitive inhibitor of mutant V600E and wild type B-Raf kinases (IC50s = 31 and 100 nM, respectively). It inhibits cell proliferation in a variety of cell lines expressing B-Raf V600E and synergizes strongly with taxol, vinblastine, and oxaliplatin in inhibiting the...
| Keywords: | RG-7204, Ro 51-85426, Vemurafenib,... |
| Application: | B-Raf kinase (mutant V600E and wild type) inhibitor |
| CAS | 918504-65-1 |
| MW: | 489.9 D |
From 60.00€
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FLLL32
Item number: Cay10638-25
FLLL32 is a cell-permeable analog of curcumin (Cay-81025) that inhibits JAK2-mediated phosphorylation of STAT3 on Tyr705 in cancer cells (IC50 = ~5 µM). It blocks signaling from IFN-alpha or IL-6 through JAK2/STAT3 and induces apoptosis in several types of cancer cells. FLLL32 does not interfere with...
| Keywords: | JAK2 Inhibitor X, (2E,2'E)-1,1'-cyclohexylidenebis[3-(3,4-dimethoxyphenyl)]-2-propen-1-one |
| Application: | STAT3 inhibitor |
| CAS | 1226895-15-3 |
| MW: | 464.6 D |
From 53.00€
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StemRegenin 1
Item number: Cay10625-1
Extending the pluripotency of hematopoietic stem cells (HSC) is of key importance to the application of stem cell therapies in a variety of diseases. Loss of the expression of the cell surface proteins CD34 and CD133 is one marker of HSC differentiation and thus often monitored in assays to test potential compounds...
| Keywords: | SR1, 4-[2-[[2-benzo[b]thien-3-yl-9-(1-methylethyl)-9H-purin-6-yl]amino]ethyl]-phenol |
| Application: | Aryl hydrocarbon receptor inhibitor |
| CAS | 1227633-49-9 |
| MW: | 429.5 D |
From 39.00€
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