- Search results for Cay10354-50
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15 products were found matching "Cay10354-50"!
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Item number: Cay35450-50
Lansoprazole sulfone N-oxide is a potential impurity found in commercial preparations of the proton pump inhibitor lansoprazole. It is a degradation product formed under oxidative conditions.Formal Name: 2-[[[3-methyl-1-oxido-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole. CAS Number:...
Keywords: | 2-[[[3-methyl-1-oxido-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole |
Application: | Lansoprazole potential impurity found in commercial preparations |
CAS | 953787-54-7 |
MW: | 401.4 D |
From 146.00€
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Item number: Cay15450-500
11beta-PGF1beta is the stereoisomer of PGF1alpha with both C-9 and C-11 hydroxyls inverted. There are no published reports on the biological activity of this compound. 11beta-PGF1beta is the stereoisomer of PGF1alpha with both C-9 and C-11 hydroxyls inverted.Formal Name:...
Keywords: | 11-epi PGF1beta, 11beta-PGF1beta, 9beta,11beta-PGF1alpha, 9beta,11beta,15S-trihydroxy-prost-13E-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 37785-86-7 |
MW: | 356.5 D |
From 77.00€
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Item number: Cay10350-100
Protein Arginine Methyltransferases (PRMTs) are S-adenosyl-L-methionine-dependent enzymes that catalyze post-translational modification of arginine residues by methylation in three different ways: monomethylation, symmetric dimethylation, or asymmetric dimethylation at terminal arginine guanidino nitrogen atoms....
Keywords: | Interferon receptor 1-bound protein 4, Interferon receptor 1-bound protein 4, Protein arginine N-methyltransferase 1,... |
Application: | Enzyme activity |
Expressed in: | E.coli |
MW: | 69,2 kD |
391.00€
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Item number: Cay17354-500
Trimethylamine N-oxide (TMAO) is a metabolite of choline, phosphatidylcholine, and L-carnitine (Cay-21489). It is formed by gut microbiota-mediated metabolism of choline, phosphatidylcholine, and L-carnitine to TMA followed by oxidation of TMA by flavin-containing monooxygenase 3 (FMO3) in the liver. Dietary...
Keywords: | NSC 408426, TMAO, N,N-dimethyl-methanamine, N-oxide |
Application: | TMA oxidition FMO4 product, atherosclerosis risk factor |
CAS | 1184-78-7 |
MW: | 75.1 D |
From 43.00€
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Item number: Cay16354-500
SU 1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1, IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases. It effectively blocks signaling through VEGFR2 both in vitro and in vivo. SU 1498 is used to study the role of VEGFR2...
Keywords: | AG-1498, Tyrphostin SU 1498, (2E)-2-cyano-3-[4-hydroxy-3,5-bis(1-methylethyl)phenyl]-N-(3-phenylpropyl)-2-propenamide |
Application: | VEGFR2 inhibitor |
CAS | 168835-82-3 |
MW: | 390.5 D |
From 46.00€
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Item number: Cay10534-500
(R)-Bromoenol lactone-d7 ((R)-BEL-d7) is intended for use as an internal standard for the quantification of (R)-BEL by GC- or LC-MS. The phospholipases are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components. The calcium-independent...
Keywords: | (R)-BEL-d7, 6E-(bromoethylene)tetrahydro-3R-(1-naphthalenyl-2,3,4,5,6,7,8-d7)-2H-pyran-2-one |
Application: | GC/LC standard |
MW: | 324.2 D |
From 50.00€
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Item number: Cay13054-500
2-(3-pyridyl)-Benzimidazole is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 2-(3-pyridinyl)-1H-benzimidazole. CAS Number: 1137-67-3. Synonyms: G 514, NSC 62610. Molecular Formula: C12H9N3. Formula Weight: 195.2. Purity: >98%. Formulation: (Request formulation change), A crystalline...
Keywords: | G 514, NSC 62610, 2-(3-pyridinyl)-1H-benzimidazole |
Application: | Synthetic intermediate, pharmaceutical synthesis |
CAS | 1137-67-3 |
MW: | 195.2 D |
From 24.00€
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Item number: Cay14035-50
3-Bromomethcathinone is a designer drug which has been identified in products marketed as bath salts or plant food. The physiological properties of this compound are not known. This product is intended for forensic and research applications.Formal Name: 1-(3-bromophenyl)-2-(methylamino)-1-propanone,...
Keywords: | 3-BMC, 1-(3-bromophenyl)-2-(methylamino)-1-propanone, monohydrochloride |
Application: | Analytical reference standard, 'bath salt' designer drug |
CAS | 676487-42-6 |
MW: | 278.6 D |
From 266.00€
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Item number: Cay35410-50
Desethoxy quetiapine is an active metabolite of the atypical antipsychotic quetiapine (Cay-14152). It is formed from quetiapine primarily by the cytochrome P450 (CYP) isoform CYP3A5 and binds to dopamine D2 receptors (IC50 = 1,330 nM). Desethoxy quetiapine (20 and 40 mg/kg) reduces climbing induced by the dopamine...
Keywords: | O-Desalkylquetiapine, 4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazineethanol, dihydrochloride |
Application: | Quetiapine active metabolite |
CAS | 329218-14-6 |
MW: | 412.4 D |
From 225.00€
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COVID-19 Research
Item number: Cay30354-50
Remdesivir is a prodrug form of the antiviral nucleotide analog GS-443902. Upon entry into cells, remdesivir is metabolized into the intermediate metabolite GS-441524 (Cay-30469), which is then further metabolized to the active nucleotide triphosphate GS-443902 that induces RNA chain termination and inhibits viral...
Keywords: | GS-5734, N-[(S)-hydroxyphenoxyphosphinyl)-L-alanine, 2-ethylbutyl ester, 6-ester with... |
Application: | GS-441524 prodrug, SARS type antiviral |
CAS | 1809249-37-3 |
MW: | 602.6 D |
From 146.00€
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Item number: Cay11304-50
Poly(ADP-ribose) polymerase (PARP) is a critical DNA repair enzyme involved in DNA single-strand break repair via the base excision repair pathway. PARP1 is activated by DNA damage. Inhibiting its activity has been linked to synthetic lethality and loss of either of the breast cancer susceptibility genes, BRCA1 and...
Keywords: | IND 71677, Iniparib, 4-iodo-3-nitro-benzamide |
Application: | PARP1 inhibitor |
CAS | 160003-66-7 |
MW: | 292 D |
From 161.00€
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Item number: Cay14304-50
PNU 120596 is a positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor (nAChR), increasing agonist-evoked calcium flux (EC50 = 216 nM). It has no detectable effect on alpha4beta2, alpha3beta4, or alpha9beta10 nAChRs. PNU-120596 increases the frequency of ACh-evoked GABAergic...
Keywords: | NSC 216666, N-(5-chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea |
Application: | Positive allosteric CHRNA7 modulator |
CAS | 501925-31-1 |
MW: | 311.7 D |
From 66.00€
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