- Search results for Cay10354-25
Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
10 products were found matching "Cay10354-25"!
Close filters
Filter by:
No results were found for the filter!
Item number: Cay15425-25
Ticagrelor is a reversible antagonist of the platelet purinergic P2Y12 receptor (Ki = 14 nM, IC50 = 1.8 µM), which is the main receptor responsible for ADP-induced platelet aggregation. It functions by directly changing the conformation of the P2Y12 receptor to inhibit ADP binding. Formulations containing ticagrelor...
Keywords: | AR-C 126532XX, AZD 6140,... |
Application: | P2Y12 receptor antagonist |
CAS | 274693-27-5 |
MW: | 522.6 D |
From 43.00€
*
Item number: Cay10325-1
Chemokine-Like Receptor 1 (CMKLR1) is a G protein-coupled receptor relevant to the cellular chemotaxis of dendritic cells and macrophages. This receptor is also expressed in brain, liver, lung, and kidney tissues. Chemerin, or TIG2, has been identified as the natural ligand for this receptor. Resolvin E1 has also...
Keywords: | Anti-CMKLR1, Anti-CHEMR23, Anti-Chemokine-like receptor 1, Anti-Chemokine-like receptor 1, Anti-G-protein coupled receptor... |
Application: | FC, IF, IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
422.00€
*
Item number: Cay15324-25
SMER3 is a selective inhibitor of Skp1-Cullin-F-box (SCF)MET30 ubiquitin ligase, an E3 ligase that regulates transcription, cell-cycle control, and immune response. It is a small molecule enhancer of rapamycin (Cay-13346), in that it enhances yeast cell lethality in response to rapamycin. SMER3, at 5 µM, upregulates...
Keywords: | MET30 Antagonist, SCFMET30 Inhibitor, 9H-indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one |
Application: | Skp1-Cullin-F-box (SCF)Met30 ubiquitin ligase inhibitor |
CAS | 67200-34-4 |
MW: | 224.2 D |
From 109.00€
*
Item number: Cay13354-250
Hexacosanoic acid is a 26-carbon saturated (26:0) very-long-chain fatty acid. Plasma levels of hexacosanoic acid are increased in a mouse model of adrenoleukodystrophy, a peroxisomal disorder. Increased levels of hexacosanoic acid in red blood cells or in plasma positively correlated with atherosclerotic risk...
Keywords: | C26:0, Ceric Acid, Cerotic Acid, NSC 4205, hexacosanoic acid |
Application: | Bioactive lipid assays |
CAS | 506-46-7 |
MW: | 396.7 D |
From 84.00€
*
Item number: Cay15325-25
STO-609 is a calcium/calmodulin-dependent protein kinase kinase (CaMKK) inhibitor (IC50s = 120 and 40 ng/ml for CaMKKalpha and CaMKKbeta, respectively). It is selective for CaMKKs over CaMKI, CaMKII, CaMKIV, MLCK, PKC, PKA, and p42 MAPK (IC50s = > 10,000 ng/ml for all). STO-609 inhibits phosphorylation of CaMKI and...
Keywords: | 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid, monoacetate |
CAS | 1173022-21-3 |
MW: | 374.4 D |
From 43.00€
*
Item number: Cay15403-25
CAY10683 is a potent histone deacetylase (HDAC) inhibitor isolated from the cyanobacterium Symploca. It inhibits HDAC2 and HDAC6 with IC50 values of 0.119 and 434 nM, respectively, and is without effect against HDAC4 (IC50 = >1,000 nM). CAY10683 inhibits the growth of HCT116 colon cancer cells and HuT-78 cutaneous T...
Keywords: | Santacruzamate A, N-[4-oxo-4-[(2-phenylethyl)amino]butyl]-carbamic acid, ethyl ester |
Application: | HDAC inhibitor |
CAS | 1477949-42-0 |
MW: | 278.4 D |
From 64.00€
*
Item number: Cay35410-25
Desethoxy quetiapine is an active metabolite of the atypical antipsychotic quetiapine (Cay-14152). It is formed from quetiapine primarily by the cytochrome P450 (CYP) isoform CYP3A5 and binds to dopamine D2 receptors (IC50 = 1,330 nM). Desethoxy quetiapine (20 and 40 mg/kg) reduces climbing induced by the dopamine...
Keywords: | O-Desalkylquetiapine, 4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazineethanol, dihydrochloride |
Application: | Quetiapine active metabolite |
CAS | 329218-14-6 |
MW: | 412.4 D |
From 225.00€
*
Item number: Cay20354-25
Copanlisib is an inhibitor of class I phosphoinositide 3-kinase (PI3K) isoforms (IC50s = 0.5, 3.7, 6.4, and 0.7 nM for alpha, beta, gamma, and delta, respectively). It is weakly active or inactive against numerous other kinases. Copanlisib is effective in vivo when administered intravenously, inhibiting PI3K...
Keywords: | BAY 80-6946,... |
Application: | Class I PI3K isoform inhibitor |
CAS | 1032568-63-0 |
MW: | 480.5 D |
From 82.00€
*
Lipid-based Drug Delivery Tools
Item number: Cay35425-1
Cayman's Lipid Nanoparticle (LNP-102) Exploration Kit is intended to serve as a starting point for laboratories to explore the feasibility of using LNPs for their individual application without the need for specialized equipment. Optimal preparation conditions for the encapsulation of oligonucleotides with LNPs must...
Application: | SM-102-containing LNP preparation |
354.00€
*
Item number: Cay10005072-500
CAY10455 is a labeled analog of arachidonoyl ethanolamide (anandamide, AEA) that is non-fluorescent when outside the cell. Upon transport into the cell interior, it is cleaved by esterases to give a bright fluorescence at 530 nm. CAY10455 uptake into C6 glioma cells is inhibited by AEA and its analogs, and...
Keywords: | SKM 4-45-1,... |
Application: | Bioactive lipid assays |
CAS | 290374-09-3 |
MW: | 804.9 D |
From 77.00€
*