5 products were found matching "Cay11158"!
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Diphenhydramine (hydrochloride)
Item number: Cay11158-100
Diphenhydramine (DPH) is a first generation antihistamine that is a potent antagonist of the histamine H1 receptor (Ki = 11.7 nM using human recombinant receptors). DPH readily crosses the blood-brain barrier and produces diverse cognitive and psychomotor effects. DPH also antagonizes muscarinic cholinergic...
| Keywords: | DPH, 2-(diphenylmethoxy)-N,N-dimethyl-ethanamine, monohydrochloride |
| Application: | H1 receptor antagonist |
| CAS | 147-24-0 |
| MW: | 291.8 D |
From 43.00€
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Ganglioside GT1b (bovine) (sodium salt)
Item number: Cay15588-5
Ganglioside GT1b is a trisialoganglioside that is characterized by having two sialic residues linked to the inner galactose unit. It binds to the neurotoxins botulinum toxin serotype A (BTxA), BTxA heavy chain, and tetanus toxin with IC50 values of 11, 0.74, and 7.2 µM, respectively. Ganglioside GT1b-containing...
| Keywords: | Ganglioside G1 Mixture |
| Application: | Trisialoganglioside |
| MW: | 2126.3 D |
From 145.00€
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Ramipril
Item number: Cay15558-1
Ramipril is a prodrug form of the angiotensin-converting enzyme (ACE) inhibitor ramiprilat (Cay-15557). Ramipril (2.5 mg/kg per day, p.o.) reduces systolic blood pressure in spontaneously hypertensive rats. It reduces aortic valve backscatter and improves aortic flow in a rabbit model of aortic valve stenosis....
| Keywords: | HOE 498,... |
| Application: | Angiotensin-converting enzyme (ACE) inhibitor |
| CAS | 87333-19-5 |
| MW: | 416.5 D |
From 84.00€
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AZD 8330
Item number: Cay11588-1
AZD 8330 is a selective allosteric inhibitor of MEK1/2 (IC50 = 7 nM). It blocks phosphorylation of ERK1/2 and inhibits proliferation of certain cancer cells. AZD 8330 is orally bioavailable, inhibits ERK phosphorylation in vivo, and reduces tumor growth in a Calu-6 nude rat xenograft model.Formal Name:...
| Keywords: | ARRY-424704, 2-[(2-fluoro-4-iodophenyl)amino]-1,6-dihydro-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-3-pyridinecarboxamide |
| Application: | MEK inhibitor |
| CAS | 869357-68-6 |
| MW: | 461.2 D |
From 84.00€
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Doxepin (hydrochloride)
Item number: Cay15888-1
Doxepin is a tricyclic antidepressant that binds to the serotonin (5-HT) transporter (SERT) and norepinephrine transporter (NET, Kds = 68 and 29.5 nM, respectively). It is a histamine H1 receptor antagonist (Ki = 1.23 nM). Doxepin selectively binds to SERT and NET over the dopamine transporter (DAT, Kd = 12,100 nM)...
| Keywords: | 3-(dibenz[b,e]oxepin-11(6H)-ylidene)-N,N-dimethyl-1-propanamine, monohydrochloride |
| Application: | Histamine, serotonin, adrenergic, muscarinic receptor antagonist, Norepinephrine reuptake inhibitor |
| CAS | 1229-29-4 |
| MW: | 315.8 D |
From 50.00€
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