Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
CHI-HF-210DcR3-C100 | 100 µg | - | - |
3 - 9 business days* |
457.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The extracellular domain of human DcR3 (aa 24-300) is fused to the N-terminus of the Fc region of... more
Product information "DcR3 (human):Fc (human) (rec.)"
The extracellular domain of human DcR3 (aa 24-300) is fused to the N-terminus of the Fc region of human IgG1. DcR3 protein function: Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis. [The UniProt Consortium] Decoy receptor 3 (DcR3, TNFRSF6B, M68) is a member of the TNF receptor superfamily. DcR3 shares sequence identity with OPG (31%), TNF-RII (29%) and Fas (17%) and is expressed in a variety of different tissues and at high levels in many malignant tumors. Ligands of DcR3 include Fas ligand, homologous to lymphotoxin showing inducible expression and competing with HSV glycoprotein D for herpes virus entry mediator (a receptor expressed by T lymphocytes), TNF-like molecule 1A and heparan sulfate proteoglycans. DcR3 modulates the function of T cells, dendritic cells and macrophages. DcR3/Fc fusion proteins can bind to human and mouse B cells and suppress the activation of B cells.
Keywords: | M68, DcR3, DCR3, TNFRSF6B, Decoy receptor 3, Decoy receptor for Fas ligand, Tumor necrosis factor receptor superfamily member 6B |
Supplier: | Chimerigen Laboratories |
Supplier-Nr: | HF-210DcR3 |
Properties
Conjugate: | No |
Host: | Hamster cells |
Species reactivity: | human |
Purity: | >98% |
Format: | Lyophilized |
Database Information
KEGG ID : | K05143 | Matching products |
UniProt ID : | O95407 | Matching products |
Gene ID | GeneID 8771 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed