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Item number: Cay16247-5

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly specific and potent allosteric inhibitors of HIV-1 reverse transcriptase. Dapivirine, a diarylpyrimidine derivative of the potent NNRTI efavirenz (Cay-14412), inhibits HIV-1 reverse transcriptase with an IC50 value of 24 nM in vitro. It impedes the...

Keywords:	R147681, TMC120, 4-[[4-[(2,4,6-trimethylphenyl)amino]-2-pyrimidinyl]amino]-benzonitrile
Application:	Reverse transcriptase inhibitor, Antiviral agent
CAS	244767-67-7
MW:	329.4 D

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