DNQX

DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 µM for AMPA and kainate receptors, respectively versus IC50 = 40 µM for NMDA receptors). This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors. DNQX does not stimulate a robust long-term potentiation in the hippocampus.Formal Name: 1,4-dihydro-6,7-dinitro-2,3-quinoxalinedione. CAS Number: 2379-57-9. Synonyms: 6,7-Dinitroquinoxaline-2,3-dione, FG 9041. Molecular Formula: C8H4N4O6. Formula Weight: 252.1. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: 12 mg/ml, DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml, DMSO: 5 mg/ml. lambdamax: 273, 334 nm. SMILES: O=C1C(NC2=CC([N+]([O-])=O)=C([N+]([O-])=O)C=C2N1)=O. InChi Code: InChI=1S/C8H4N4O6/c13-7-8(14)10-4-2-6(12(17)18)5(11(15)16)1-3(4)9-7/h1-2H,(H,9,13)(H,10,14). InChi Key: RWVIMCIPOAXUDG-UHFFFAOYSA-N.