DMABA-d10 NHS ester

DMABA-d10 NHS ester
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay11219-1 1 mg -

6 - 10 business days*

145.00€
Cay11219-5 5 mg -

6 - 10 business days*

639.00€
Cay11219-10 10 mg -

6 - 10 business days*

1,131.00€
 
DMABA-d10 NHS ester is intended for use in combination with DMABA NHS ester (Cay-11216) as a... more
Product information "DMABA-d10 NHS ester"
DMABA-d10 NHS ester is intended for use in combination with DMABA NHS ester (Cay-11216) as a derivatizing reagent for PE lipids in order to facilitate MS characterization and to quantify relative changes in their abundance. DMABA-d10 and DMABA NHS esters have been shown to facilitate the characterization of PE lipids via electrospray mass spectrometry by providing a common precursor ion scan for diacyl, ether, and plasmalogen PE lipids. Furthermore, application of split-and-pool methodology allows for relative changes in endogenous PE lipid levels between control and treated samples to be measured. Phosphatidylethanolamine (PE) lipids are important components of cell membranes and biochemical pathways of fatty acid synthesis that contain abundant polyunsaturated fatty acyl groups. Oxidation of these phospholipids may be linked to various human diseases. DMABA NHS ester is a reagent that reacts with the primary amine group of PE lipids. This facilitates the use of electrospray tandem mass spectrometry for the detection of diacyl, ether, and plasmalogen PE lipids that cannot be readily observed otherwise.Formal Name: 4-[di(methyl-d3)amino]-benzoic-2,3,5,6-d4 acid, 2,5-dioxo-1-pyrrolidinyl ester. CAS Number: 1175002-05-7. Molecular Formula: C13H4D10N2O4. Formula Weight: 272.3. Purity: >99% deuterated forms (d1-d10). Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, DMSO:PBS (pH 7.2) (1:30): 0.03 mg/ml. lambdamax: 235, 322 nm. SMILES: O=C(CC1)N(OC(C2=C([2H])C([2H])=C(N(C([2H])([2H])[2H])C([2H])([2H])[2H])C([2H])=C2[2H])=O)C1=O. InChi Code: InChI=1S/C13H14N2O4/c1-14(2)10-5-3-9(4-6-10)13(18)19-15-11(16)7-8-12(15)17/h3-6H,7-8H2,1-2H3/i1D3,2D3,3D,4D,5D,6D. InChi Key: FNGFZOAQGYOQTG-ZGYYUIRESA-N.
Keywords: 4-[di(methyl-d3)amino]-benzoic-2,3,5,6-d4 acid, 2,5-dioxo-1-pyrrolidinyl ester
Supplier: Cayman Chemical
Supplier-Nr: 11219

Properties

Application: PE lipid derivatization
MW: 272.3 D
Formula: C13H4D10N2O4
Purity: >99% deuterated forms (d1-d10)
Format: Crystalline Solid

Database Information

CAS : 1175002-05-7| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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