41 products were found matching "AG-40A-0178"!
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DNER (extracellular domain) (mouse):Fc (human, rec.)
Item number: AG-40A-0177-C010
Signal peptide and extracellular domain of mouse DNER (amino acids 1-640) are fused at the C-terminus to the Fc portion of human IgG. Liquid. 0.2µm-filtered solution in PBS. DNER is an activator of the Notch1 pathway. It mediates neuron-glia interaction during astrocytogenesis.
| Keywords: | BET, UNQ262/PRO299, Delta and Notch-like Epidermal Growth Factor-related Receptor |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | mouse |
From 237.00€
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IL-37 (human) (rec.) (His)
Item number: AG-40A-0174Y-3010
Protein function: Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares...
| Keywords: | IL37, FIL1Z, IL-37, IL-1H, IL-1X, IL-1H4, IL-1F7, IL-1RP1, IL-1 zeta, FIL1 zeta, Interleukin-37, Interleukin-23,... |
| Application: | Cell culture |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 30 kD |
From 248.00€
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Progranulin (human) (rec.) (untagged)
Item number: AG-40A-0188Y-C050
Signal peptide and human progranulin (aa 1-593) is untagged. Reflects the native sequence with no additional aa. Activates phospho-ERK1/2 in neuronal mouse P19 cells. Regulates food intake and body weight. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as...
| Keywords: | GRN, Proepithelin, PEPI, PC Cell-derived Growth Factor |
| Application: | Cell culture |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 74 kD |
From 215.00€
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Nampt (Visfatin/PBEF) (mouse, rec.) (His)
Item number: AG-40A-0017-C050
Mouse Nampt (visfatin/PBEF) (amino acids 1-491) is fused at the C-terminus to a His-tag. Shows adipogenic effects in stimulated differentiating 3T3-L1 cells. Liquid. 0.2µm-filtered solution in PBS, pH 7.2. Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an...
| Keywords: | Pre-B Cell Colony Enhancing Factor 1, PBEF1, Nicotinamide Phosphoribosyltransferase |
| Application: | Bioassays |
| Expressed in: | E.coli |
| Origin: | mouse |
| MW: | 52 kD |
440.00€
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DLK1 (mouse):Fc (human) (rec.)
Item number: AG-40A-0107Y-3010
Signal peptide and extracellular domain of mouse DLK1 (aa 1-305) are fused at the C-terminus to the Fc portion of human IgG1. Biological Activity: Inhibits adipogenesis of 3T3L-1 cells. Induces Sox-9 in 3T3L-1 cells. The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1,...
| Keywords: | Replaces AG-40A-0107, Protein Delta Homolog 1, Preadipocyte Factor 1, Pref-1, Dlk, Dlk1 |
| Application: | Cell culture |
| Expressed in: | Human cells |
| Origin: | mouse |
| MW: | 75 kD |
From 275.00€
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Progranulin (mouse) (rec.) (untagged)
Item number: AG-40A-0189Y-C010
Signal peptide and mouse progranulin (aa 1-589) is untagged. Reflects the native sequence with no additional aa. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell...
| Keywords: | Grn, Proepithelin, PEPI, PC Cell-derived Growth Factor |
| Application: | Cell culture |
| Expressed in: | Human cells |
| Origin: | mouse |
| MW: | 70 kD |
From 209.00€
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FGF-23 (mouse):Fc (human) (rec.)
Item number: AG-40A-0128Y-3010
Recombinant protein. Mouse FGF-23 (aa25-251) is fused at the C-terminus to the Fc portion of human IgG1. Activates ERK and FRS2alpha phosphorylation in Klotho expressing cells. Source/Host: HEK 293 cells. Purity: >90% (SDS-PAGE). Lyophilized. Contains PBS. FGF-23 (Fibroblast growth factor 23) is a regulator of...
| Keywords: | Fibroblast Growth Factor 23, Tumor-derived Hypophosphatemia-inducing Factor |
| Expressed in: | Human cells |
| Origin: | mouse |
| MW: | 45 kD |
From 204.00€
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Lipocalin-2 (rat, rec.)
Item number: AG-40A-0108-C010
Rat lipocalin-2 (amino acids 1-198) is fused at the C-terminus to a FLAG(R)-tag. Liquid. 0.2µm-filtered solution in PBS. Lipocalin-2 is an iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development.
| Keywords: | Siderocalin, Oncogene 24p3, Neutrophil Gelatinase-associated Lipocalin, NGAL |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | rat |
| MW: | 25 kD |
193.00€
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DLK2 (human):Fc (human, rec.)
Item number: AG-40A-0158-C010
Signal peptide and the extracellular domain of human DLK2 (amino acids 1-306) are fused at the C-terminus to the Fc portion of human IgG. Liquid. 0.2µm-filtered solution in PBS. DLK2 regulates adipogenesis.
| Keywords: | Protein Delta Homolog 2, Epidermal Growth Factor-like Protein 9 |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 70 kD |
From 275.00€
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CD137L, Soluble (human) (rec.)
Item number: AG-40A-0198T-C050
The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and...
| Keywords: | 4-1BBL, TNFSF9, 4-1BB ligand, Tumor necrosis factor ligand superfamily member 9 |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~23 kD |
418.00€
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DLL1 (mouse):Fc (human) (rec.)
Item number: AG-40A-0148Y-C010
The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a...
| Keywords: | Delta-like Protein 1, Delta 1 |
| Application: | Bioassays |
| Expressed in: | Human cells |
| MW: | 100 kD |
From 171.00€
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DNER (extracellular domain) (human) (rec.)
Item number: AG-40A-0137Y-C010
Signal peptide and extracellular domain of human DNER (aa 1-640) are fused at the C-terminus with a FLAG(R)-tag. Lyophilized. Contains PBS. DNER is an activator of the Notch1 pathway. It mediates neuron-glia interaction during astrocytogenesis.
| Keywords: | BET, DNER, Delta and Notch-like epidermal growth factor-related receptor |
| Application: | Notch1 pathway activator |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 100 kD |
From 259.00€
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