DLK1 (human, rec.)

Signal peptide and extracellular domain of human DLK1 (amino acids 1-303) are fused at the C-terminus to a FLAG(R)-tag. Liquid. 0.2µm-filtered solution in PBS. DLK1 (Protein delta homolog 1, Preadipocyte factor 1, Pref-1) is a regulator of adipocyte differentiation found in serum and urine. DLK1 might be a decoy ligand. Serum or plasma levels of soluble DLK1 affect negatively or positively adipogenesis and control mesenchymal cell fate. DLK1 is frequently upregulated in myelodysplastic syndrome (MDS) patients compared to non-leukemic individuals.