29 products were found matching "AG-CR1-3576"!

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AZ191
AZ191

Item number: AG-CR1-3657-M001

White to off-white solid. Soluble in DMSO (5mg/ml), ethanol (2mg/ml) or DMF (2mg/ml). Cell permeable azaindole that inhibits the serine/threonine kinase activity of DYRK1B (IC50=17nM) with 5-fold and 110-fold selectivity against the related family members DYRK1A and DYRK2, respectively, Used as a probe to elucidate...
Keywords: N-[2-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]-4-(1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-pyrimidinamine
Application: Cell permeable DYRK1B inhibitor
CAS 1594092-37-1
MW: 429,5 D
28.00€ * From 25.20€ *
Review
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Colcemid
Colcemid

Item number: AG-CR1-3567-M001

Semisynthetic from colchicine (Prod. No. AG-CN2-0048). Anti-cancer compound - Cell synchronization agent - Used as a drug in chemotherapy by synchronizing tumor cells at metaphase, the radiosensitive stage of the cell cycle - Microtubule assembly inhibitor - Depolymerizes microtubules and limits microtubule...
Keywords: Demecolcine, BRN 2822892
Application: Cell synchronization agent
CAS 477-30-5
MW: 371,4 D
39.00€ * From 35.10€ *
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MTSSL
MTSSL

Item number: AG-CR1-3573-M050

Highly reactive, thiol-specific spin-label. Specific conformational probe of thiol site structure by its minimal rotational freedom and distance from the covalent disulfide linkage to the macromolecule under study. Used to label cysteine residues in proteins (site-directed labeling, SDS-labeling). Allows protein...
Keywords: Mts-SL, MTSL, (1-Oxyl-2,2,5,5-tetramethylpyrroline-3- methyl)methanethiosulfonate, Otmpmms
Application: Protein labeling, Thiol-specific spin-label
Host: Synthetic
CAS 81213-52-7
MW: 264,3 D
83.00€ * From 74.70€ *
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Rosiglitazone
Rosiglitazone

Item number: AG-CR1-3570-M010

Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and...
Keywords: BRL 49653, HSDB 7555, TDZ 01
Application: PPAR-gamma agonist
Host: Synthetic
CAS 122320-73-4
MW: 357,4 D
33.00€ * From 29.70€ *
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Suramin . sodium salt
Suramin . sodium salt

Item number: AG-CR1-3575V-G001

Potent ATPase inhibitor [1]. Potent competitive inhibitor of reverse transcriptase. Shows anti-HIV activity [2, 3]. Anticancer compound [4, 5, 15]. Protein kinase C (PKC) inhibitor [4]. Potent inhibitor of melanoma heparanase and tumor cell metastasis [6]. Non-specific growth factors inhibitor (including PDGF, EGF,...
Keywords: Germanin, NSC 34936, SK 24728
Application: Potent ATPase inhibitor, Antineoplastic, Antiprotozoal
CAS 129-46-4
MW: 1429.1 D
55.00€ * From 49.50€ *
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Suramin . hexasodium salt
Suramin . hexasodium salt

Item number: AG-CR1-3575-M050

Potent ATPase inhibitor [1]. Potent competitive inhibitor of reverse transcriptase. Shows anti-HIV activity [2, 3]. Anticancer compound [4, 5, 15]. Protein kinase C (PKC) inhibitor [4]. Potent inhibitor of melanoma heparanase and tumor cell metastasis [6]. Non-specific growth factors inhibitor (including PDGF, EGF,...
Keywords: Germanin, NSC 34936, SK 24728
Application: ATPase Inhibitor
Host: Synthetic
CAS 129-46-4
MW: 1429,1 D
88.00€ * From 79.20€ *
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Etoposide (5x100mg)
Etoposide (5x100mg)

Item number: AG-CR1-3572-M025

Potent anti-cancer compound. Induces apoptosis in normal and tumor cell lines. DNA Topoisomerase II activity inhibitor. Increases Topo II-mediated DNA breakage primarily by inhibiting the ability of the enzyme to religate cleaved nucleic acid molecules. Does not lead to immediate block of DNS synthesis, induces a...
Keywords: VP-16-213, NSC 141540
Application: Apoptosis Inducer
Host: Semisynthetic
CAS 33419-42-0
MW: 588,6 D
33.00€ * From 29.70€ *
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Amlexanox
Amlexanox

Item number: AG-CR1-3579-M010

Soluble in DMSO or dimethylformamide. Antiallergic. Anti-inflammatory. Antagonizes the angiogenic and mitogenic activity of FGF-1 through S100A13. Inhibits FGF-1 release. Binds to HSP90. Inhibits C-terminal chaperone activity. Induces an increase in nonsense-containing mRNAs amount in treated cells, leading to...
Keywords: 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid, AA 673, Amoxanox, CHX 3674
Application: TBK1 / IKKE inhibitor
CAS 68302-57-8
MW: 298,3 D
66.00€ * From 59.40€ *
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Rosiglitazone, maleate
Rosiglitazone, maleate

Item number: AG-CR1-3571-M025

Same activities as rosaglitazone (Prod. No. AG-CR1-3570) but different formulation. Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more...
Keywords: BRL 49653C, Rosiglitazone XR, Avandia
Application: PPAR-gamma agonist
Host: Synthetic
CAS 155141-29-0
55.00€ * From 49.50€ *
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L-NMMA . monoacetate
L-NMMA . monoacetate

Item number: AG-CR1-3578-M005

Synthetic. Endothelium-derived relaxing factor inhibitor. Inhibits the generation of NO from arginine. Competitive, irreversible non-selective inhibitor of all three NOS I, II, and III isoforms (eNOS, iNOS and nNOS). Inhibits the synthesis of nitric oxide (NO) in a dose-dependent and enantiospecific fashion. Useful...
Keywords: NG-Monomethyl-L-arginine . monoacetate
Application: NOS inhibitor
CAS 53308-83-1
MW: 248,3 D
22.00€ * From 19.80€ *
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Salsalate
Salsalate

Item number: AG-CR1-3574-G001

Nonacetylated salicylate - Non-steroidal anti-inflammatory drug (NSAID) - Reduces pain and inflammation caused by conditions such as rheumatoid arthritis, osteoarthritis and related rheumatic conditions - Prostaglandin synthesis inhibitor in vivo - Inactivates cyclooxygenase-1 (COX-1) and -2 (COX-2) -...
Keywords: Salicylsalicylic acid, NSC 49171, BRN 2590908, 2-Hydroxy-2-carboxyphenyl ester-benzoic acid
Application: Prodrug, Metabolic studies
CAS 552-94-3
MW: 258,2 D
33.00€ * From 29.70€ *
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PLX4720
PLX4720

Item number: AG-CR1-3577-M005

Synthetic. Potent and selective cell permeable B-Raf (V600E) and c-Raf-1 (Y340D/Y341D) inhibitor. Antitumor compound. ERK phosphorylation is potently inhibited exclusive in B-Raf(V600E)-bearing tumor cell lines.
Keywords: N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
Application: B-Raf (V600E) / c-Raf-1 (Y340D/Y341D) inhibitor
CAS 918505-84-7
MW: 413,8 D
94.00€ * From 84.60€ *
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