- Search results for AG-CR1-3576
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29 products were found matching "AG-CR1-3576"!
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-10 %
Item number: AG-CR1-3657-M001
White to off-white solid. Soluble in DMSO (5mg/ml), ethanol (2mg/ml) or DMF (2mg/ml). Cell permeable azaindole that inhibits the serine/threonine kinase activity of DYRK1B (IC50=17nM) with 5-fold and 110-fold selectivity against the related family members DYRK1A and DYRK2, respectively, Used as a probe to elucidate...
Keywords: | N-[2-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]-4-(1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-pyrimidinamine |
Application: | Cell permeable DYRK1B inhibitor |
CAS | 1594092-37-1 |
MW: | 429,5 D |
28.00€
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From 25.20€
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-10 %
Item number: AG-CR1-3567-M001
Semisynthetic from colchicine (Prod. No. AG-CN2-0048). Anti-cancer compound - Cell synchronization agent - Used as a drug in chemotherapy by synchronizing tumor cells at metaphase, the radiosensitive stage of the cell cycle - Microtubule assembly inhibitor - Depolymerizes microtubules and limits microtubule...
Keywords: | Demecolcine, BRN 2822892 |
Application: | Cell synchronization agent |
CAS | 477-30-5 |
MW: | 371,4 D |
39.00€
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From 35.10€
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-10 %
Item number: AG-CR1-3573-M050
Highly reactive, thiol-specific spin-label. Specific conformational probe of thiol site structure by its minimal rotational freedom and distance from the covalent disulfide linkage to the macromolecule under study. Used to label cysteine residues in proteins (site-directed labeling, SDS-labeling). Allows protein...
Keywords: | Mts-SL, MTSL, (1-Oxyl-2,2,5,5-tetramethylpyrroline-3- methyl)methanethiosulfonate, Otmpmms |
Application: | Protein labeling, Thiol-specific spin-label |
Host: | Synthetic |
CAS | 81213-52-7 |
MW: | 264,3 D |
83.00€
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From 74.70€
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-10 %
Item number: AG-CR1-3570-M010
Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and...
Keywords: | BRL 49653, HSDB 7555, TDZ 01 |
Application: | PPAR-gamma agonist |
Host: | Synthetic |
CAS | 122320-73-4 |
MW: | 357,4 D |
33.00€
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From 29.70€
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-10 %
Item number: AG-CR1-3575V-G001
Potent ATPase inhibitor [1]. Potent competitive inhibitor of reverse transcriptase. Shows anti-HIV activity [2, 3]. Anticancer compound [4, 5, 15]. Protein kinase C (PKC) inhibitor [4]. Potent inhibitor of melanoma heparanase and tumor cell metastasis [6]. Non-specific growth factors inhibitor (including PDGF, EGF,...
Keywords: | Germanin, NSC 34936, SK 24728 |
Application: | Potent ATPase inhibitor, Antineoplastic, Antiprotozoal |
CAS | 129-46-4 |
MW: | 1429.1 D |
55.00€
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From 49.50€
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-10 %
Item number: AG-CR1-3575-M050
Potent ATPase inhibitor [1]. Potent competitive inhibitor of reverse transcriptase. Shows anti-HIV activity [2, 3]. Anticancer compound [4, 5, 15]. Protein kinase C (PKC) inhibitor [4]. Potent inhibitor of melanoma heparanase and tumor cell metastasis [6]. Non-specific growth factors inhibitor (including PDGF, EGF,...
Keywords: | Germanin, NSC 34936, SK 24728 |
Application: | ATPase Inhibitor |
Host: | Synthetic |
CAS | 129-46-4 |
MW: | 1429,1 D |
88.00€
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From 79.20€
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-10 %
Item number: AG-CR1-3572-M025
Potent anti-cancer compound. Induces apoptosis in normal and tumor cell lines. DNA Topoisomerase II activity inhibitor. Increases Topo II-mediated DNA breakage primarily by inhibiting the ability of the enzyme to religate cleaved nucleic acid molecules. Does not lead to immediate block of DNS synthesis, induces a...
Keywords: | VP-16-213, NSC 141540 |
Application: | Apoptosis Inducer |
Host: | Semisynthetic |
CAS | 33419-42-0 |
MW: | 588,6 D |
33.00€
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From 29.70€
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-10 %
Item number: AG-CR1-3579-M010
Soluble in DMSO or dimethylformamide. Antiallergic. Anti-inflammatory. Antagonizes the angiogenic and mitogenic activity of FGF-1 through S100A13. Inhibits FGF-1 release. Binds to HSP90. Inhibits C-terminal chaperone activity. Induces an increase in nonsense-containing mRNAs amount in treated cells, leading to...
Keywords: | 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid, AA 673, Amoxanox, CHX 3674 |
Application: | TBK1 / IKKE inhibitor |
CAS | 68302-57-8 |
MW: | 298,3 D |
66.00€
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From 59.40€
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-10 %
Item number: AG-CR1-3571-M025
Same activities as rosaglitazone (Prod. No. AG-CR1-3570) but different formulation. Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more...
Keywords: | BRL 49653C, Rosiglitazone XR, Avandia |
Application: | PPAR-gamma agonist |
Host: | Synthetic |
CAS | 155141-29-0 |
55.00€
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From 49.50€
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-10 %
Item number: AG-CR1-3578-M005
Synthetic. Endothelium-derived relaxing factor inhibitor. Inhibits the generation of NO from arginine. Competitive, irreversible non-selective inhibitor of all three NOS I, II, and III isoforms (eNOS, iNOS and nNOS). Inhibits the synthesis of nitric oxide (NO) in a dose-dependent and enantiospecific fashion. Useful...
Keywords: | NG-Monomethyl-L-arginine . monoacetate |
Application: | NOS inhibitor |
CAS | 53308-83-1 |
MW: | 248,3 D |
22.00€
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From 19.80€
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-10 %
Item number: AG-CR1-3574-G001
Nonacetylated salicylate - Non-steroidal anti-inflammatory drug (NSAID) - Reduces pain and inflammation caused by conditions such as rheumatoid arthritis, osteoarthritis and related rheumatic conditions - Prostaglandin synthesis inhibitor in vivo - Inactivates cyclooxygenase-1 (COX-1) and -2 (COX-2) -...
Keywords: | Salicylsalicylic acid, NSC 49171, BRN 2590908, 2-Hydroxy-2-carboxyphenyl ester-benzoic acid |
Application: | Prodrug, Metabolic studies |
CAS | 552-94-3 |
MW: | 258,2 D |
33.00€
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From 29.70€
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-10 %
Item number: AG-CR1-3577-M005
Synthetic. Potent and selective cell permeable B-Raf (V600E) and c-Raf-1 (Y340D/Y341D) inhibitor. Antitumor compound. ERK phosphorylation is potently inhibited exclusive in B-Raf(V600E)-bearing tumor cell lines.
Keywords: | N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide |
Application: | B-Raf (V600E) / c-Raf-1 (Y340D/Y341D) inhibitor |
CAS | 918505-84-7 |
MW: | 413,8 D |
94.00€
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From 84.60€
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