D-myo-Inositol-1,3,4,6-tetraphosphate (ammonium salt)

The inositol phosphates (IPs) are a family of molecules produced by altering the phosphorylation status of each of the six carbons on the cyclic inositol structure. They act as second messengers, regulating a wide array of cellular functions. D-myo-inositol-1,3,4,6-tetraphosphate(Ins(1,3,4,6)-P4) largely acts an intermediate, serving as substrate for inositol-1,3,4,6-tetraphosphate 5-kinase to produce inositol-1,3,4,5,6-pentaphosphate, or inositol-1,3,4,6-tetraphosphate 2-kinase to give inositol-1,2,3,4,6-pentaphosphate. These inositol pentaphosphates can be further phosphorylated to produce inositol-1,2,3,4,5,6-hexakisphosphate, or phytic acid, which serves diverse roles in eukaryotic tissues. Ins(1,3,4,6)-P4 is a poor activator of the inositol 1,4,5-trisphospate receptor in vitro. Other functions of this IP remain to be elucidated.Formal Name: D-myo-inositol-1,3,4,6-tetrakis(dihydrogen phosphate), tetraammonium salt. CAS Number: 142507-74-2. Synonyms: Ins(1,3,4,6)-P4, 1,3,4,6-IP4. Molecular Formula: C6H12O18P4 . 4NH4. Formula Weight: 568.2. Purity: >95%. Formulation: (Request formulation change), A lyophilized powder. Solubility: PBS (pH 7.2): 50 mg/ml, Water: 50 mg/ml. SMILES: O[C@H]1[C@H](OP([O-])(O)=[O+])[C@@H](OP([O-])(O)=O)[C@@H](O)[C@@H](OP([O-])(O)=O)[C@@H]1OP([O-])(O)=O.[NH4+].[NH4].[NH4+].[NH4+]. InChi Code: InChI=1S/C6H16O18P4.4H3N/c7-1-3(21-25(9,10)11)5(23-27(15,16)17)2(8)6(24-28(18,19)20)4(1)22-26(12,13)14,,,,/h1-8H,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20),4*1H3/t1-,2+,3?,4?,5?,6?,,,,. InChi Key: DOJNAPODMFHFNA-GUBBRYCUSA-N.