- Search results for Cay10007945
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9 products were found matching "Cay10007945"!
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Item number: Cay10007945-5
Sphinganine (d18:0) is a precursor of ceramide and sphingosine as well as a substrate of sphingosine kinases, which generate sphinganine-1-phosphate. Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins, as well as in some cancers. Sphinganine can block protein kinase C...
Keywords: | D-erythro-Dihydrosphingosine, D-erythro-Sphinganine, Dihydro-D-erythro Sphingosine, Dihydrosphingosine, Sphinganine,... |
Application: | Sphingolipid studies |
CAS | 764-22-7 |
MW: | 301.5 D |
From 48.00€
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Item number: Cay10794-5
Agonists of the vitamin D receptor are used to suppress parathyroid hormone (PTH) synthesis and secretion in the treatment of hyperparathyroidism associated with renal failure. 22-Oxacalcitriol is an analog of calcitriol that, like calcitriol, is a receptor-active form of vitamin D3 which effectively blocks PTH...
Keywords: | Maxacalcitrol,... |
Application: | VDR ligand |
CAS | 103909-75-7 |
MW: | 418.6 D |
From 86.00€
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Lipid-based Drug Delivery Tools
Item number: Cay10007947-5
D-erythro Lysosphingomyelin is a bioactive sphingolipid. It is an agonist of sphingosine-1-phosphate receptor 1 (S1P1), S1P2, and S1P3 (EC50s = 167.7, 368.1, and 482.6 nM, respectively, for the human receptors). D-erythro Lysosphingomyelin is also an agonist of the orphan receptor ovarian cancer G protein-coupled...
Keywords: | D-erythro Lyso SM(18:1), D-erythro Sphingosine-1-Phosphocholine (d18:1), D-erythro-Sphingophosphorylcholine,... |
Application: | Bioactive Lipid Assays |
CAS | 1670-26-4 |
MW: | 464.6 D |
From 121.00€
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Lipid-based Drug Delivery Tools
Item number: Cay10007946-5
C16 Sphingomyelin is a naturally occurring sphingolipid. Levels of C16 sphingomyelin are elevated in the prefrontal cortex and cerebellum in a rat model of diabetes induced by streptozotocin (STZ, Cay-13104), as well as in the liver in mouse models of Niemann-Pick type C1 disease. Plasma levels of C16 sphingomyelin...
Keywords: | N-Palmitoyl-D-erythro-Sphingosylphosphorylcholine, Palmitoyl Sphingomyelin, SM(d18:1/16:0), Sphingomyelin (d18:1/16:0),... |
Application: | Bioactive Lipid Assays |
CAS | 6254-89-3 |
MW: | 703 D |
From 94.00€
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Item number: Cay10007974-5
FK-506 is a potent immunosuppressant that forms a high affinity complex (Ki = 0.2 nM) with FK-506 binding protein 12 (FKBP12). This complex inhibits the activity of the calcium/calmodulin-dependent protein phosphatase, calcineurin, leading to disruption of T-cell activation. Synthetic ligand of FKBP (SLF) is a...
Keywords: | Synthetic Ligand of FKBP, 1-(3,3-dimethyl-1,2-dioxopentyl)-(2S)-2-piperidinecarboxylic acid,... |
Application: | FK-506 analog |
CAS | 195513-96-3 |
MW: | 524.7 D |
From 123.00€
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Item number: Cay10007904-5
2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the central cannabinoid (CB1) receptor. It is present at relatively high levels in the central nervous system and is the most abundant molecular species of monoacylglycerol found in rat brain. Monoacylglycerol lipase (MAGL) hydrolyzes 2-AG to arachidonic...
Keywords: | 1-S-Arachidonoyl-1-mercapto-2,3-propanediol, 5Z,8Z,11Z,14Z-eicosatetraenyl,1-thio glycerol |
Application: | Bioactive lipid assays |
CAS | 1309664-54-7 |
MW: | 394.6 D |
From 39.00€
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Item number: Cay10007294-5
Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase. Arachidonoyl-N-methyl amide is an analog of...
Keywords: | N-methyl-5Z,8Z,11Z,14Z-eicosatetraenamide |
Application: | Bioactive lipid assays |
CAS | 156910-29-1 |
MW: | 317.5 D |
From 56.00€
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COVID-19 Research
Item number: Cay10007964-5
E-64c is an active metabolite of the protease inhibitor E-64d (Cay-13533). E-64c inhibits the cysteine proteases cathepsin B, cathepsin H, and papain but not the serine proteases trypsin, chymotrypsin, or elastase. It reduces the autocatalytic activity of the foot-and-mouth-disease virus (FMDV) leader protease when...
Keywords: | Loxistatin Acid, NSC 694279,... |
Application: | Cysteine protease inhibitor |
CAS | 76684-89-4 |
MW: | 314.4 D |
From 84.00€
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Item number: Cay10007094-5
7-chlorothieno[2,3-c]Pyridine is a synthetic intermediate useful for pharmaceutical synthesis.CAS Number: 28948-58-5. Molecular Formula: C7H4ClNS. Formula Weight: 169.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml,...
Keywords: | 7-chloro-thieno[2,3-c]pyridine |
Application: | Synthetic intermediate, pharmaceutical synthesis |
CAS | 28948-58-5 |
MW: | 169.6 D |
From 35.00€
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