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D-AP5
D-AP5

Item number: Cay14539-10

D-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist (Kd = 1.4 µM) that competitively inhibits the glutamate binding site of NMDA receptors. Whereas D-AP5 is the active (-)-stereoisomer, its (+)-isomer (L-AP5) demonstrates considerably less potent NMDA receptor antagonist activity. AP5 has been...
Keywords: D-2-Amino-5-Phosphonovaleric Acid, D-APV, 5-phosphono-D-norvaline
Application: NMDA receptor antagonist
CAS 79055-68-8
MW: 197.1 D
From 77.00€ *
Review
N-(p-amylcinnamoyl) Anthranilic Acid
N-(p-amylcinnamoyl) Anthranilic Acid

Item number: Cay14531-100

N-(p-amylcinnamoyl) Anthranilic acid (ACA) is a channel blocker that acts on several transient receptor potential (TRP) channels, including TRPM2, TRPM8, and TRPC6 (IC50 = 1.7, 3.8, and 2.3 µM, respectively). It is a weak inhibitor of TRPV1. ACA is also an inhibitor of phospholipase A2, blocking the release of...
Keywords: ACA, 2-[[1-oxo-3-(4-pentylphenyl)-2-propen-1-yl]amino]-benzoic acid
Application: TRP channel blocker
CAS 110683-10-8
MW: 337.4 D
From 84.00€ *
Review