- Search results for Cay14601
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7 products were found matching "Cay14601"!
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Item number: Cay14601-10
(±)-Cromakalim is a prototypical activator of the ATP-sensitive potassium channel, SUR2-Kir6, that displays anti-ischemic (EC25 = 8.9 µM) and cardioprotective (IC50 = 0.03 µM) effects in rat hearts. (±)-Cromakalim has also been shown to relax bladder smooth muscle in vitro. It has been used to investigate potassium...
Keywords: | BRL 34915, (3R,4S)-rel-3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-6-carbonitrile |
Application: | SUR2-Kir6 activator |
CAS | 94470-67-4 |
MW: | 286.3 D |
From 163.00€
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Item number: Cay14460-1
During apoptosis, activated caspase-3 cleaves several substrates, including poly(ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-pNA is a para-nitro aniline chromophore cleaved by caspases (Km = 18, 11, 32, 180, and 12 µM for caspases-1, -3, -4, -6, and -7, respectively). It...
Keywords: | Ac-Asp-Glu-Val-Asp-pNA, N-acetyl-L-alpha-aspartyl-L-alpha-glutamyl-L-valyl-N-(4-nitrophenyl)-L-alpha-asparagine |
Application: | Caspase substrate |
CAS | 189684-50-2 |
MW: | 638.6 D |
From 43.00€
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Item number: Cay14609-1
(±)-Anatoxin A is a bicyclic amine isolated from the blue-green alga A. aquae that displays high affinity for nicotinic acetylcholine receptors (Kd = 0.1-0.2 µM). It binds alpha4beta2- and alpha7-type nicotinic receptors with Ki values of 1.3 nM and 1.8 µM, respectively, and stimulates [3H]-dopamine release from...
Keywords: | 1-(9-azabicyclo[4.2.1]non-2-en-2-yl)-ethanone, 2-butenedioate |
Application: | Neuronal nicotinic acetylcholine receptor agonist |
CAS | 1219922-30-1 |
MW: | 281.3 D |
327.00€
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Item number: Cay14604-1
The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferases G9a and G9a-like protein (GLP) can mono- or dimethylate lysine 9 on histone 3, contributing to early embryogenesis, genomic imprinting, and lymphocyte...
Keywords: | 2-(4,4-difluoropiperidin-1-yl)-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine |
Application: | EHMT1 / EHMT2 inhibitor |
CAS | 1481677-78-4 |
MW: | 546.7 D |
From 84.00€
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Item number: Cay14606-1
FBBBE is a derivatized fluorescein compound that is used to detect the production hydrogen peroxide (H2O2) by cells. Intracellular H2O2, but not extracellular H2O2, initiates the conversion of FBBBE to fluorescein, resulting in an increase in intracellular fluorescence (excitation/emission maxima: 480/512 nm).Formal...
Keywords: | Fluorescein bis (benzyl boronic ester),... |
Application: | Fluorometric intracellular H2O2 measurement |
CAS | 1522117-83-4 |
MW: | 764.5 D |
From 43.00€
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Item number: Cay14607-1
Philanthotoxin 74 (PhTx-74) is a synthetic analog of the naturally-occurring wasp venom toxin philanthotoxin-4,3,3. It is a subtype-selective AMPA receptor antagonist that inhibits homomeric GluR1 and GluR3 as well as heteromeric GluR1/2 receptors (80-100% of glutamate-evoked currents inhibited at 100 µM). It...
Keywords: | PhTx-74, N-[7-[(4-aminobutyl)amino]heptyl]-4-hydroxy-alphaS-[(1-oxobutyl)amino]-benzenepropanamide, dihydrochloride |
Application: | Forensic studies |
CAS | 1227301-51-0 |
MW: | 507.5 D |
From 92.00€
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Item number: Cay14650-1
13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is a metabolite of PGE2 (Cay-14010) and the primary PGE2 metabolite in plasma. It is formed from PGE2 via a 15-keto PGE2 intermediate by 15-oxo-PG Delta13 reductase. Unlike PGE2, 13,14-dihydro-15-keto PGE2 does not bind effectively to the PGE2...
Keywords: | 13,14-dihydro-15-keto PGE2, 9,15-dioxo-11alpha-hydroxy-prost-5Z-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 363-23-5 |
MW: | 352.5 D |
From 104.00€
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