11 products were found matching "AG-40A-0168"!

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Progranulin (human) (rec.)
Progranulin (human) (rec.)

Item number: AG-40A-0068Y-C010

Signal peptide and human progranulin (aa 1-593) are fused at the C-terminus to a FLAG(R)-tag. Activates ERK phosphorylation in THP-1 and MCF10A cells and induces cell migration of THP-1 monocytic leukemia cells. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such...
Keywords: GRN, Proepithelin, PEPI, PC Cell-derived Growth Factor
Application: Cell culture
Expressed in: Human cells
Origin: human
MW: 76 kD
From 187.00€ *
Review
DLL1 (human):Fc (human) (rec.)
DLL1 (human):Fc (human) (rec.)

Item number: AG-40A-0116Y-C010

Signal peptide and extracellular domain of human DLL1 (aa 1-545) are fused at the C-terminus to the Fc portion of human IgG1. Lyophilized. Contains PBS. DLL1 (Delta-like protein, Delta1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and...
Keywords: DLL1, Delta1, H-Delta-1, Delta-like protein 1, Drosophila Delta homolog
Application: Bioassay
Expressed in: Hamster cells
Origin: human
MW: 100 kD
From 286.00€ *
Review
Progranulin (human) (rec.) (untagged)
Progranulin (human) (rec.) (untagged)

Item number: AG-40A-0188Y-C050

Signal peptide and human progranulin (aa 1-593) is untagged. Reflects the native sequence with no additional aa. Activates phospho-ERK1/2 in neuronal mouse P19 cells. Regulates food intake and body weight. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as...
Keywords: GRN, Proepithelin, PEPI, PC Cell-derived Growth Factor
Application: Cell culture
Expressed in: Human cells
Origin: human
MW: 74 kD
From 215.00€ *
Review
Progranulin (rat) (rec.) (untagged)
Progranulin (rat) (rec.) (untagged)

Item number: AG-40A-0196Y-C010

Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the...
Keywords: Proepithelin, PEPI, PC Cell-derived Growth Factor
Application: Bioassays
Expressed in: Human cells
Origin: rat
MW: 73 kD
From 215.00€ *
Review
Contactin-6 (human):Fc (human, rec.)
Contactin-6 (human):Fc (human, rec.)

Item number: AG-40A-0156-C010

Human contactin-6 (amino acids 1-999) is fused at the C-terminus to the Fc portion of human IgG. Induces Hes-1 in 3T3L-1 cells. Liquid. 0.2µm-filtered solution in PBS. Contactin-6 is a member of the contactins, which mediate cell surface interactions during nervous system development. Contactin-6 has a key role in...
Keywords: Neural Recognition Molecule NB-3, CNTN6
Application: Bioassays
Expressed in: Human cells
Origin: human
MW: 150 kD
From 215.00€ *
Review
Progranulin (mouse) (rec.) (untagged)
Progranulin (mouse) (rec.) (untagged)

Item number: AG-40A-0189Y-C010

Signal peptide and mouse progranulin (aa 1-589) is untagged. Reflects the native sequence with no additional aa. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell...
Keywords: Grn, Proepithelin, PEPI, PC Cell-derived Growth Factor
Application: Cell culture
Expressed in: Human cells
Origin: mouse
MW: 70 kD
From 209.00€ *
Review
FGF-23 (mouse):Fc (human) (rec.)
FGF-23 (mouse):Fc (human) (rec.)

Item number: AG-40A-0128Y-3010

Recombinant protein. Mouse FGF-23 (aa25-251) is fused at the C-terminus to the Fc portion of human IgG1. Activates ERK and FRS2alpha phosphorylation in Klotho expressing cells. Source/Host: HEK 293 cells. Purity: >90% (SDS-PAGE). Lyophilized. Contains PBS. FGF-23 (Fibroblast growth factor 23) is a regulator of...
Keywords: Fibroblast Growth Factor 23, Tumor-derived Hypophosphatemia-inducing Factor
Expressed in: Human cells
Origin: mouse
MW: 45 kD
From 204.00€ *
Review
Lipocalin-2 (rat, rec.)
Lipocalin-2 (rat, rec.)

Item number: AG-40A-0108-C010

Rat lipocalin-2 (amino acids 1-198) is fused at the C-terminus to a FLAG(R)-tag. Liquid. 0.2µm-filtered solution in PBS. Lipocalin-2 is an iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development.
Keywords: Siderocalin, Oncogene 24p3, Neutrophil Gelatinase-associated Lipocalin, NGAL
Application: Bioassays
Expressed in: Human cells
Origin: rat
MW: 25 kD
193.00€ *
Review
DLK2 (human):Fc (human, rec.)
DLK2 (human):Fc (human, rec.)

Item number: AG-40A-0158-C010

Signal peptide and the extracellular domain of human DLK2 (amino acids 1-306) are fused at the C-terminus to the Fc portion of human IgG. Liquid. 0.2µm-filtered solution in PBS. DLK2 regulates adipogenesis.
Keywords: Protein Delta Homolog 2, Epidermal Growth Factor-like Protein 9
Application: Bioassays
Expressed in: Human cells
Origin: human
MW: 70 kD
From 275.00€ *
Review
CD137L, Soluble (human) (rec.)
CD137L, Soluble (human) (rec.)

Item number: AG-40A-0198T-C050

The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and...
Keywords: 4-1BBL, TNFSF9, 4-1BB ligand, Tumor necrosis factor ligand superfamily member 9
Application: Bioassays
Expressed in: Human cells
Origin: human
MW: ~23 kD
418.00€ *
Review
DLL1 (mouse):Fc (human) (rec.)
DLL1 (mouse):Fc (human) (rec.)

Item number: AG-40A-0148Y-C010

The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a...
Keywords: Delta-like Protein 1, Delta 1
Application: Bioassays
Expressed in: Human cells
MW: 100 kD
From 171.00€ *
Review