Conoidin A

Conoidin A
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay15605-25 25 mg -

6 - 10 business days*

77.00€
Cay15605-50 50 mg -

6 - 10 business days*

114.00€
Cay15605-100 100 mg -

6 - 10 business days*

149.00€
Cay15605-250 250 mg -

6 - 10 business days*

333.00€
 
Peroxiredoxins are a widely conserved family of enzymes that function in antioxidant defense and... more
Product information "Conoidin A"
Peroxiredoxins are a widely conserved family of enzymes that function in antioxidant defense and act in redox signaling pathways. Increased expression of human peroxiredoxin is associated with cancer, cardiovascular dysfunction, and neurodegeneration. Conoidin A inactivates peroxiredoxins by covalently binding to the catalytic cysteine on the enzyme. It has been shown to inhibit peroxiredoxin II (IC50 = 23 µM) in the parasite T. gondii and peroxiredoxin I in the hookworm A. ceylanicum. At 5 µM, conoidin A can also inhibit the glucose oxidase-mediated hyperoxidation of mammalian peroxiredoxin I and II, but not peroxiredoxin III.Formal Name: 2,3-bis(bromomethyl)-quinoxaline 1,4-dioxide. CAS Number: 18080-67-6. Molecular Formula: C10H8Br2N2O2. Formula Weight: 348.0. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml, DMSO: 20 mg/ml. lambdamax: 240, 278, 391 nm. SMILES: [O-][N+]1=C(CBr)C(CBr)=[N+]([O-])C2=C1C=CC=C2. InChi Code: InChI=1S/C10H8Br2N2O2/c11-5-9-10(6-12)14(16)8-4-2-1-3-7(8)13(9)15/h1-4H,5-6H2. InChi Key: DQKNFTLRMZOAMG-UHFFFAOYSA-N.
Keywords: 2,3-bis(bromomethyl)-quinoxaline 1,4-dioxide
Supplier: Cayman Chemical
Supplier-Nr: 15605

Properties

Application: Peroxiredoxin inhibitor
MW: 348 D
Formula: C10H8Br2N2O2
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 18080-67-6| Matching products
KEGG ID : K13279 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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