- Search results for AG-CR1-0081
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3 products were found matching "AG-CR1-0081"!
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Item number: AG-CR1-0081-M005
Cell permeable, potent, selective, non-transition state and non-competitive and gamma-secretase inhibitor. Notch processing inhibitor. Only weakly affects presenilinase activity.
Keywords: | (2S)-2-([(3,5-Difluorophenyl)acetyl]amino)-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide |
Application: | gamma-secretase inhibitor |
CAS | 209986-17-4 |
MW: | 490,5 D |
From 88.00€
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Item number: AG-CR1-0088-M001
Potent cell permeable and selective inhibitor of yeast NAD-dependent histone deacetylase (HDAC) Sir2p. Displays higher activity in vivo than in vitro. Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated...
Keywords: | 1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one, 1-Naphthalen propanoic acid |
Application: | HDAC inhibitor |
CAS | 5690-03-9 |
MW: | 198,2 D |
From 33.00€
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Item number: AG-CR1-0087-M001
Isozyme selective inhibitor of protein kinase Cbeta (PKCbeta) - PKCbeta-I and PKCbeta-II isozyme inhibitor - Amelioriates diabetic retinopathy, diabetic peripheral neuropathy and diabetic nephropathy - Anti-cancer and anti-angiogenic compound - Suppresses glucose-induced adhesion of human monocytes to endothelial...
Keywords: | Ruboxistaurin |
Application: | PKCbeta inhibitor |
CAS | 169939-93-9 |
MW: | 505,1 D |
From 77.00€
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