11 products were found matching "Cay580110-1"!

Perphenazine sulfoxide is an active metabolite of the typical antipsychotic perphenazine (Cay-20735). It is formed via oxidation of perphenazine. Perphenazine sulfoxide selectively binds to dopamine D2 and alpha1-adrenergic receptors (alpha1-ARs) over alpha2-ARs (Kis= 5.9, 24, and 683 nM, respectively) in rat brain....

Cayman's cAMP assay is a very sensitive competitive ELISA that permits cAMP measurements within the standard curve range of 0.078-10 pmol/ml, typically with a sensitivity (80% B/B0) of 0.1 pmol/ml once samples and standards have been acetylated prior to analysis. This assay has been validated with culture media,...

Fraxetin is a coumarin that has been found in F. bungeana and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH, Cay-14805) radicals, ABTS (Cay-27317) radicals, and hydrogen peroxide in cell-free assays (IC50s = 44.1, 37.4, and 40.5 µM, respectively). Fraxetin selectively reduces...

Cayman's HLA-DR (alpha and beta chains) ELISA Kit is an immunometric assay (i.e., sandwich) that can be used for the quantification of the HLA-DR complex in cell lysates. The standard curve spans the range of 0.63-40 ng/ml, with a limit of quantification of 1.25 ng/ml.Synonyms: HLA Class II, HLA-DR (alpha and beta...

This EIA so called Easy Sampling EIA kit works with any sample collected on any kind of protease inhibitors, without extraction but a simple dilution. Ghrelin discovered in 1999, is fast becoming an endocrinology target of the millennium. Ghrelin, identified in rat stomach as an endogenous ligand for the GH...

The USP1 deubiquitinating enzyme, which regulates the DNA translesion synthesis (TLS) and Fanconi anemia (FA) DNA damage response pathways by deubiquitinating the central players of these pathways, is activated by the WD40-repeat containing UAF1 protein through formation of a stable USP1-UAF1 protein complex. ML-323...

AMT is a potent, relatively selective inhibitor of iNOS with a Ki of 4.2 nM in mouse macrophages. It inhibits other isoforms of NOS, but at higher concentrations, the IC50 values for rat nNOS and bovine eNOS are 34 and 150 nM, respectively.Formal Name: 5,6-dihydro-6-methyl-4H-1,3-thiazin-2-amine, hydrochloride. CAS...

(±)-Cotinine-d3 is intended for use as an internal standard for the quantification of cotinine by GC- or LC-MS. Cotinine is an alkaloid found in tobacco and a major metabolite of nicotine (Cay-16535). It is formed by oxidation of nicotine by the cytochrome P450 (CYP) isoform CYP2A6.Formal Name:...

P70 ribosomal S6 kinase (S6K1) is a serine/threonine kinase which is activated by insulin and growth factors through PI3K and mTORC1 signaling pathways. PF-04708671 is a specific, cell-permeable inhibitor of S6K1 (IC50 = 160 nM). It does not inhibit S6K2, MSK, or RSK, or many other unrelated kinases, under...

Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that upon phosphorylation binds to immunoreceptor tyrosine-based activation motifs of FcRgamma chains and mediates downstream signaling related to platelet function and inflammation. R788 is a prodrug of R406 (Cay-11422), an inhibitor of Syk (Ki = 30...

This kit contains all reagents necessary for simple one-step purification of 8-isoprostane from most biological samples.Synonyms: iPF2alpha-III, 8-epi Prostaglandin F2alpha, 8-iso Prostaglandin F2alpha. Origin: Animal/Mouse.