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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C4200-10D.10 | 10 µg | - | - |
3 - 19 business days* |
1,037.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Chk1 is a 56kD Serine/Threonine protein kinase that was originally identified in fission yeast to... more
Product information "Chk1, active, Recombinant, Human (CHEK1, Cell Cycle Checkpoint Kinase)"
Chk1 is a 56kD Serine/Threonine protein kinase that was originally identified in fission yeast to play a role in activation of the DNA damage checkpoint in the G2 phase of the cell cycle (1). Chk1 appears to function downstream of several of the known fission yeast checkpoint gene products, including that encoded by Rad3, a gene with sequence similarity to the ATM gene mutated in patients with ataxia telangiectasia (2). Source: Recombinant full-length human Chk1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The gene accession number is NM_001274. Molecular Mass: The approximate molecular weight is 82kD (see Figure 1 below). Activity: The specific activity of Chk1 was determined to be 195 nmol/min/mg using a synthetic peptide substrate (KKKVSRSGLYRSPSMPENLNRPR). Storage: This product is stable at -70°C for at least 6 months from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.
Keywords: | CHK1, CHEK1, EC=2.7.11.1, Checkpoint kinase-1, CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Serine/threonine-protein kinase Chk1 |
Supplier: | United States Biological |
Supplier-Nr: | C4200-10D |
Properties
Conjugate: | No |
Species reactivity: | human |
Format: | Highly Purified |
Database Information
KEGG ID : | K02216 | Matching products |
UniProt ID : | O14757 | Matching products |
Gene ID | GeneID 1111 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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