Cell Meter(TM) Caspase 9 Activity Apoptosis Assay Kit (Red Fluorescence)

Cell Meter(TM) Caspase 9 Activity Apoptosis Assay Kit (Red Fluorescence)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABD-22817 100 tests -

3 - 8 business days*

279.00€
 
Our Cell Meter(TM) assay kits are a set of tools for monitoring cellular functions. There are a... more
Product information "Cell Meter(TM) Caspase 9 Activity Apoptosis Assay Kit (Red Fluorescence)"
Our Cell Meter(TM) assay kits are a set of tools for monitoring cellular functions. There are a variety of parameters that can be used. This particular kit is designed to monitor cell apoptosis by measuring caspase 9 activity. Caspase 9 is a member of the CED-3 subfamily. Activated Caspase-9 cleaves downstream caspases such as caspase-3, -6 and -7, initiating the caspase cascade. It is essential for apoptosis during normal development of the central nervous system. Caspase 9 is proven to have selectivity for the peptide sequence Leu-Glu-His-Asp (LEHD). This kit uses Ac-LEHD-ProRed(TM) as a fluorogenic indicator for caspase 9 activity. Cleavage of ProRed(TM) by caspase 9 generates strongly fluorescent ProRed(TM) which is monitored at Ex/Em = 530/620 nm. The kit provides all the essential components. The assay is robust and can be readily adapted for high throughput screening. It can be used to either quantify the activated caspase 9 activities in apoptotic cells or screen the caspase 9 inhibitors. Quite a few labs have used this kit for high throughput screenings.
Keywords: MCH6, CASP9, APAF-3, CASP-9, ICE-LAP6, Caspase-9, EC=3.4.22.62, Caspase-9 subunit p10, Caspase-9 subunit p35, Apoptotic protease Mch-6, ICE-like apoptotic protease 6, Apoptotic protease-activating factor 3
Supplier: AAT Bioquest
Supplier-Nr: 22817

Properties

Application: Caspase-9 assays
Format: Homog.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Signal Word: Warning
Caution
Our products are for laboratory research use only: Not for administration to humans!
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