Cell Meter(TM) Caspase 8 Activity Apoptosis Assay Kit * Green Fluorescence*

Cell Meter(TM) Caspase 8 Activity Apoptosis Assay Kit * Green Fluorescence*
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABD-22798 1 kit -

3 - 8 business days*

279.00€
 
Our Cell Meter(TM) assay kits are a set of tools for monitoring cellular functions. There are a... more
Product information "Cell Meter(TM) Caspase 8 Activity Apoptosis Assay Kit * Green Fluorescence*"
Our Cell Meter(TM) assay kits are a set of tools for monitoring cellular functions. There are a variety of parameters that can be used to monitor cell apoptosis. This particular kit is designed to monitor cell apoptosis by measuring caspase 8 activity. Caspase 8 is a caspase protein, encoded by the CASP8 gene. Caspase 8 also plays an important role in neurodegenerative diseases such as Huntington disease. Caspase 8 is proven to have substrate selectivity for the peptide sequence Ile-Glu-Thr-Asp (IETD). This kit uses (Ac-IETD)2-R110 as a fluorogenic indicator for caspase 8 activity. Cleavage of rhodamine 110 (R110) peptides by caspase 8 generates strongly fluorescent R110 which is monitored at the emission between 520 nm and 530 nm with the excitation between 480 nm and 500 nm. This spectral feature makes the kit compatible with the FITC filter set. The kit provides all the essential components with an optimized assay protocol. The assay can be readily adapted for high throughput screenings. It can be used to either quantify the activated caspase 8 activities in apoptotic cells or screen the caspase 8 inhibitors.
Supplier: AAT Bioquest
Supplier-Nr: 22798

Properties

Application: Apoptosis studies, Caspase 8 quantification
Format: Homog.

Database Information

KEGG ID : K04398 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Signal Word: Warning
Caution
Our products are for laboratory research use only: Not for administration to humans!
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