- Search results for C2086-68F
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9 products were found matching "C2086-68F"!
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Item number: C2086-68B.100
Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth...
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
688.00€
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Item number: C2086-68Q.100
Caspase-1, also known as IL-1 beta-converting enzyme (ICE), is an enzyme that cleaves the inflammatory cytokines IL-1 beta and IL-18, releasing the mature, active peptides. Caspase-1 is important for defense against pathogens and it also is involved in the induction of apoptosis. Thymocytes from caspase-1 deficient...
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
886.00€
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Item number: C2086-66C.100
Caspase 1/ICE (Interleukin-1b Converting Enzyme) is expressed as a proenzyme of 45kD in many tissues. Upon stimulus it gets activated by proteolytic cleavage. Active Caspase 1 is a tetramer of two subunits p10 and p20 in 2,2 proportion. Caspase 1 (cystein aspartic-specific protease 1) cleaves its substrates after an...
Application: | ICC, IHC, IP, WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
863.00€
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Item number: C2086-66G.100
Capases are a highly conserved family of cysteine proteases and are synthesized as inactive zymogens, which are cleaved at Asp-x sites during apoptosis, generating large and small subunits that heterodimerize to form the active enzyme. Caspase-1 is a member of the ICE/CED-3 family of caspases and is detected in the...
Application: | ELISA, FC, WB |
Host: | Rat |
Species reactivity: | mouse |
750.00€
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Item number: C2086-66H.50
Caspase-1 is an intracellular cysteine protease, identified as a mammalian homologue to C. elegans cell death gene (ced-3). Caspase-1 has been classified as an inflammatory, rather than apoptotic caspase, due to its essential role in the cleavage of the inactive precursors of the cytokines IL-1beta and IL-18, into...
Application: | IHC, IP, WB |
Host: | Rabbit |
Species reactivity: | human |
710.00€
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Item number: C2086-66W.100
Applications:, Suitable for use in Immunohistochemistry (paraffin) and Western Blot. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 2.0ug/ml , Western Blot: 0.5-1ug/ml , Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for...
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
727.00€
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Item number: C2086-66X.100
Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth...
Application: | IHC, WB |
Host: | Mouse |
Species reactivity: | human, mouse |
662.00€
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Item number: C2086-66Y.100
Caspase-1, also known as IL-1b-converting enzyme (ICE), is an aspartic protease that plays a key role in the inflammatory response and apoptosis. The active enzyme consists of a complex of two 20kD (aa120-297) and two 10kD (aa317-404) subunits which associate following cleavage of inactive precursors. Caspase-1 is...
Keywords: | EC=3.4.22.36, Anti-Caspase-1 subunit p20, Anti-Caspase-1 subunit p10, Anti-IL-1 beta-converting enzyme, Anti-Interleukin-1... |
Application: | WB |
Host: | Goat |
Species reactivity: | human |
1,007.00€
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Item number: C2086-66G1.100
Caspase-1 plays a vital role in cleaving the inactive procytokine pro-IL-1 beta to generate the active 17kD mature form of IL-1beta, a key mediator of inflammation. Active caspase-1 (ICE) is derived a single proenzyme of 45kD. An active ICE comprises two subunits of P20 and two subunits of P10 after removal a large...
Application: | IHC, WB |
Host: | Rat |
Species reactivity: | human |
From 386.00€
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