- Search results for Cay10010743-250
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4 products were found matching "Cay10010743-250"!
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Item number: Cay10010743-500
Capsaicin is a terpene alkaloid that has been found in Capsicum and has diverse biological activities. It induces inward currents in HEK293 cells expressing rat transient receptor potential vanilloid 1 (TRPV1, EC50 = 0.64 µM at neutral pH), an effect that can be blocked by the TRPV1 inhibitor A-425619. Capsaicin (10...
Keywords: | N-[(4-hydroxy-3-methoxyphenyl)methyl]-6E-8-methyl-nonenamide |
Application: | Metabolic studies |
CAS | 404-86-4 |
MW: | 305.4 D |
From 43.00€
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Item number: Cay10010740-25
Cellular prion protein (PrPc) is a cell surface glycoprotein expressed in brain, spinal cord, and several peripheral tissues that if mutated to the protease-resistant isoform PrPSc (scrapie PrP, PrPres) can result in one of several fatal neurodegenerative diseases. Prion diseases, including mad cow disease (bovine...
Keywords: | 3-(4-Nitrophenyl)-1-phenyl-2-pyrazolin-5-one, 2,4-dihydro-5-(4-nitrophenyl)-2-phenyl-3H-pyrazol-3-one |
Application: | PrPc accumulation inhibitor |
CAS | 34320-83-7 |
MW: | 281.3 D |
From 38.00€
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Item number: Cay10010243-10
The HER2/Neu proto-oncogene is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases (RTK) which includes EGFR, HER2/Neu, HER3 and HER4. Overexpression of HER2/Neu occurs in 25-30% of human breast and ovarian cancer. AG-825 is a selective ATP-competitive inhibitor of the...
Keywords: | Tyrphostin AG-825, 3-[3-[(2-benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano-2-propenamide |
Application: | HER-2/neu inhibitor |
CAS | 149092-50-2 |
MW: | 397.5 D |
From 38.00€
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Item number: Cay10010240-25
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Olomoucine is a cdk inhibitor that acts by competing for the ATP binding site of the kinase. This purine derivative is an inhibitor for CDC2/cyclin B (IC50 = 7 µM), Cdk2/cyclin A (IC50...
Keywords: | 2-[[9-methyl-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-ethanol |
Application: | CDK inhibitor |
CAS | 101622-51-9 |
MW: | 298.3 D |
From 43.00€
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