Calreticulin (CRT) is a multifunctional, multi-compartmental protein most abundant in the ER lumen, but also found in other membrane-bound organelles, the cell surface and extracellularly. Reports of nuclear localization are likely immunostaining artifacts (1). CRT is also known as CRP-55, calregulin and HACBP (high...

Calretinin (CAB29, calbindin 2) is a calcium binding protein that belongs to calbindin family. It is mainly found in neuronal tissue, high expressed in auditory neurons. It has been implicated in as a calcium buffer, calcium sensor, and as a regulator of apoptosis. Calretinin is considered as a specific marker of...

CASQ2 (Calsequestrin 2) protein responsible for holding Calcium together with other two proteins junction and triadin at the sarcoplasmic reticulum renders the hear vulnerable to severe cardiac arrhythmias, known as CPVT (catecholaminergic polymorphic ventricular tachycardia), during physical exercise. Applications:...

Calyculin A, a polyene phosphate, was initially isolated from the marine sponge Discodermia calyx. It is a very potent, cell-permeable PP-1 and PP-2 inhibitor (IC50: 2nM and 0.5-1nM respectively, and extremely specific for PP-1 and PP2A classes of protein serine/threonine phosphatase among other acidic, alkaline...