CNQX

CNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 µM for AMPA and kainate receptors, respectively, versus IC50 = 25 µM for NMDA receptors). This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors.Formal Name: 1,2,3,4-tetrahydro-7-nitro-2,3-dioxo-6-quinoxalinecarbonitrile. CAS Number: 115066-14-3. Synonyms: 6-cyano-7-Nitroquinoxaline-2,3-dione, FG 9065. Molecular Formula: C9H4N4O4. Formula Weight: 232.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 12 mg/ml, DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml, DMSO: 5 mg/ml. lambdamax: 217, 275, 315 nm. SMILES: O=C1C(NC2=CC([N+]([O-])=O)=C(C#N)C=C2N1)=O. InChi Code: InChI=1S/C9H4N4O4/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5/h1-2H,(H,11,14)(H,12,15). InChi Key: RPXVIAFEQBNEAX-UHFFFAOYSA-N.