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CHIR124
CHIR124

Item number: Cay16553-1

Checkpoint kinase 1 (Chk1) regulates S and G2-M phase cell cycle checkpoints in response to DNA damage. CHIR124 is a cell-permeable, quinolone-based inhibitor of Chk1 (IC50 = 0.3 nM in vitro). It demonstrates high selectivity for Chk1 by displaying inhibitory values 2,000-fold higher against Chk2 (IC50 = 0.7 µM). In...
Keywords: 4-[(3S)-1-azabicyclo[2.2.2]oct-3-ylamino]-3-(1H-benzimidazol-2-yl)-6-chloro-2(1H)-quinolinone
Application: Cell-permeable Chk1 inhibitor
CAS 405168-58-3
MW: 419.9 D
From 48.00€ *
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Goat F(Ab')2 Anti-Rat IgG:SureLight(TM) R-PE
Goat F(Ab')2 Anti-Rat IgG:SureLight(TM) R-PE

Item number: Cay16653-100

Goat F(Ab')2 anti-Rat IgG conjugated to SureLight(TM) R-PE Antibody: Goat F(Ab')2 polyclonal anti-Rat IgG Dye: SureLight(TM) R-phycoerythrin (R-PE) Excitation max. lambda: 565>498 nm Emission max. lambda: 578 nm Uses: Flow cytometry, fluorescence-activated cell sorting, and protein microarraysEmission: 578 nm....
Application: Cell based assays, FC
Host: Goat
Species reactivity: rat
293.00€ *
Review