- Search results for Cay15545
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7 products were found matching "Cay15545"!
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Item number: Cay15545-5
The cystic fibrosis (CF) gene encodes a cAMP-regulated chloride channel, the CF transmembrane conductance regulator (CFTR). CFTR inhibitor-172 is a thiazolidinone that selectively blocks the CFTR channel (Ki = 300 nM) in a voltage-independent manner. It appears to directly modulate the gating of chloride at the...
Keywords: | CFTR(inh)-172, Cystic Fibrosis Transmembrane Conductance Regulator Inhibitor 172,... |
Application: | CFTR blocker |
CAS | 307510-92-5 |
MW: | 409.4 D |
From 109.00€
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Item number: Cay15544-5
FR180204 is a potent cell-permeable inhibitor of ERK1 and ERK2 (Ki = 310 and 140 nM, respectively). It is much less effective against p38alpha (IC50 = 10 µM) and does not inhibit a range of other serine/threonine or tyrosine kinases. FR180204 blocks ERK-mediated signaling from TGF-beta to AP-1 (IC50 = 3.1 µM). It...
Keywords: | ERK Inhibitor II, 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine |
Application: | Cell-permeable ERK1 / ERK2 inhibitor |
CAS | 865362-74-9 |
MW: | 327.3 D |
From 84.00€
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Item number: Cay15546-5
Aminoethoxyvinyl glycine (AVG) is an ethylene biosynthesis inhibitor and a plant growth regulator. It inhibits ethylene production in, and elongation of, maize root tips when used at a concentration of 1 µM. AVG also inhibits cystathionine beta-lyase and cystathionine gamma-lyase (Kis = 1.1 and 10.5 µM,...
Keywords: | ABG 3168, AVG, Aviglycine, (2S,3E)-2-amino-4-(2-aminoethoxy)-3-butenoic acid, monohydrochloride |
Application: | Ethylene biosynthesis inhibitor |
CAS | 55720-26-8 |
MW: | 196.6 D |
From 63.00€
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Item number: Cay15549-5
Phleomycin is a glycopeptide antibiotic from Streptomyces whose cytotoxic action results from its ability to cause DNA fragmentation. The ability of phleomycin to block mammalian cells from entering mitosis has made it useful in cancer therapy, most commonly in conjunction with other therapeutic modalities....
Keywords: | (2R,3S,4S,5R,6R)-2-(((2R,3S,4S,5S,6S)-2-(2-(6-amino-2-(3-amino-1-((2,3-diamino-3-oxopropyl)amino)-3-oxopropyl)-5-methylpyr... |
Application: | Glycopeptide antibiotic, DNA fragmentation agent |
CAS | 11006-33-0 |
MW: | 1525.5 D |
From 84.00€
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Item number: Cay15543-5
HNMPA is a cell impermeable tyrosine kinase inhibitor that blocks receptor serine and tyrosine phosphorylation, including insulin receptor tyrosine kinase activity. It does not affect protein kinase C or cyclic AMP-dependent protein kinase activities. HNMPA inhibits the insulin-stimulated autophosphorylation of the...
Keywords: | Hydroxy-2-naphthalenylmethyl Phosphonic Acid, P-(hydroxy-2-naphthalenylmethyl)-phosphonic acid |
Application: | Cell impermeable tyrosine kinase inhibitor |
CAS | 132541-52-7 |
MW: | 238.2 D |
From 43.00€
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Item number: Cay15547-25
Hoechst 33342 is a cell-permeable, benzimidazole dye that stains DNA by binding to the minor groove of adenine and thymine-rich sequences. It emits blue fluorescence (excitation 350 nm/emission maximum 461 nm) when bound to double stranded DNA and is useful as a marker of nuclei for cell cycle studies and to...
Keywords: | Bisbenzimide, HOE 33342, NSC 334072, 2'-(4-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole,... |
Application: | Blue fluorescent DNA staining, FC, Fluorescence microscopy |
CAS | 875756-97-1 |
MW: | 561.9 D |
From 48.00€
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Item number: Cay15548-25
Ramosetron is a potent and selective antagonist of the serotonin (5-HT) receptor subtype 5-HT3 (Ki = 0.06 nM). It has little or no effect at other 5-HT receptor subtypes or at adrenergic or histamine receptors. Ramosetron competitively blocks serotonin-mediated contraction of the colon. It has applications in...
Keywords: | (1-methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]-methanone, monohydrochloride |
Application: | 5-HT3 receptor antagonist |
CAS | 132907-72-3 |
MW: | 315.8 D |
From 92.00€
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