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Item number: CHI-HF-210CD80-C100

The extracellular domain of human CD80 (aa 35-242) is fused to the N-terminus of the Fc region of human IgG1. CD80 (B7-1) and CD86 (B7-2) together with their receptors CD28 and CTLA-4 constitute one of the dominant costimulatory pathways that regulate T cell and B cell responses. Although both CTLA-4 and CD28 can...

Keywords:	B7, BB1, CD80, CD28LG, Activation B7-1 antigen, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD80
Application:	Bioassays
Expressed in:	Hamster cells
Origin:	human

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