- Search results for AG-40B-0010
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6 products were found matching "AG-40B-0010"!
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Item number: AG-40B-0010-C010
(3 x 10 µg). Human CD40L (amino acids 116-261) is fused at the N-terminus to mouse ACRP30headless (amino acids 18-111) and a FLAG(R)-tag. Induces B cells activation (as demonstrated by dose-dependent upregulation of CD86) (ED50: <1ng/ml). Lyophilized. Contains PBS MultimericCD40L is a high activity construct in...
Keywords: | MegaCD40L(TM), Soluble (human, rec.), ACRP30headless:CD40L, ACRP30headless:CD154, ACRP30headless:TNFSF5, ADIPOQ-CD40L |
Application: | Bioassays |
Expressed in: | Hamster cells |
Origin: | human |
From 363.00€
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Item number: AG-40B-0100-C010
IL-36gamma (mouse) (aa 13-183) is untagged. Induces secretion of IL-6 in BMDCs. IL-36alpha (IL-1F6), IL-36beta(IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12,...
Keywords: | Il1f9, Il36g, IL-1F9, Interleukin-36 gamma, Interleukin-1 family member 9 |
Application: | IL-6 secretion induction |
Expressed in: | E.coli |
Origin: | mouse |
MW: | 17 kD |
215.00€
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Item number: AG-40B-0110-3050
The extracellular domain of mouse Notch2 (aa 26-494) (12 epidermal growth factor-like (EGF) repeats) is fused at the C-terminus to the Fc portion of human IgG1.
Keywords: | NOTCH2, NOTCH-2, neurogenic locus notch homolog protein 2, AGS2. |
Expressed in: | CHO cells |
Origin: | mouse |
MW: | 87 kD |
From 275.00€
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Item number: AG-40B-0010AF-C010
CD40 ligand (CD40L) expressed by activated T cells engages CD40 expressed by B cells and APCs. CD40L can provide signals to B cells that induce proliferation, immunoglobulin class switching and antibody secretion. CD40L has been used recently in Immunotherapy to activate tumor-infiltrated lymphocytes (TIL)....
Keywords: | CD40L, CD40LG |
Expressed in: | Hamster cells |
Origin: | human |
MW: | 3540 kD |
From 396.00€
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Item number: AG-40B-0234-3010
Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells and lymphokine activated killer cells. IL-2 also stimulates proliferation of...
Keywords: | IL-2 Switch-2 (monomeric):Fc Knobs-into-Holes (human) (rec.), Interleukin-2, T Cell Growth Factor, TCGF, IL-2 pH... |
Application: | Bioassays |
Expressed in: | Human cells |
Origin: | human, mouse |
MW: | 45+28 kD |
From 429.00€
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Item number: AG-40B-0130-3010
(3 x 10 µg). Human FasL (aa 139-281) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG(R)-tag. Lyophilized. Contains PBS. MultimericFasL (human) is a high activity construct in which two trimeric FasL are artificially linked via the collagen domain of ACRP30. This construct very effectively...
Keywords: | MegaFasL, Soluble (human) (rec.), SPA, APL, FasL, APTL, CD178, FASLG, sFasL, CD95-L, APT1LG1, FasL ICD, Fas ligand, CD95... |
Application: | FasL aggregation stimulator |
Expressed in: | Human cells |
Origin: | human, mouse |
MW: | 40 kD |
From 363.00€
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