6 products were found matching "AG-40B-0010"!

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CD40L (human) (multimeric)
CD40L (human) (multimeric)

Item number: AG-40B-0010-C010

(3 x 10 µg). Human CD40L (amino acids 116-261) is fused at the N-terminus to mouse ACRP30headless (amino acids 18-111) and a FLAG(R)-tag. Induces B cells activation (as demonstrated by dose-dependent upregulation of CD86) (ED50: <1ng/ml). Lyophilized. Contains PBS MultimericCD40L is a high activity construct in...
Keywords: MegaCD40L(TM), Soluble (human, rec.), ACRP30headless:CD40L, ACRP30headless:CD154, ACRP30headless:TNFSF5, ADIPOQ-CD40L
Application: Bioassays
Expressed in: Hamster cells
Origin: human
From 363.00€ *
Review
Interleukin-36 gamma (IL-36gamma), (mouse, rec.), untagged
Interleukin-36 gamma (IL-36gamma), (mouse, rec.), untagged

Item number: AG-40B-0100-C010

IL-36gamma (mouse) (aa 13-183) is untagged. Induces secretion of IL-6 in BMDCs. IL-36alpha (IL-1F6), IL-36beta(IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12,...
Keywords: Il1f9, Il36g, IL-1F9, Interleukin-36 gamma, Interleukin-1 family member 9
Application: IL-6 secretion induction
Expressed in: E.coli
Origin: mouse
MW: 17 kD
215.00€ *
Review
Notch2 (mouse): Fc (human) (rec.)
Notch2 (mouse): Fc (human) (rec.)

Item number: AG-40B-0110-3050

The extracellular domain of mouse Notch2 (aa 26-494) (12 epidermal growth factor-like (EGF) repeats) is fused at the C-terminus to the Fc portion of human IgG1.
Keywords: NOTCH2, NOTCH-2, neurogenic locus notch homolog protein 2, AGS2.
Expressed in: CHO cells
Origin: mouse
MW: 87 kD
From 275.00€ *
Review
CD40L (human) (multimeric) (rec.) (Animal Free)
CD40L (human) (multimeric) (rec.) (Animal Free)

Item number: AG-40B-0010AF-C010

CD40 ligand (CD40L) expressed by activated T cells engages CD40 expressed by B cells and APCs. CD40L can provide signals to B cells that induce proliferation, immunoglobulin class switching and antibody secretion. CD40L has been used recently in Immunotherapy to activate tumor-infiltrated lymphocytes (TIL)....
Keywords: CD40L, CD40LG
Expressed in: Hamster cells
Origin: human
MW: 3540 kD
From 396.00€ *
Review
IL-2 (human) (Switch-2) (monomeric):Fc-KIH (human) (rec.)
IL-2 (human) (Switch-2) (monomeric):Fc-KIH (human) (rec.)

Item number: AG-40B-0234-3010

Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells and lymphokine activated killer cells. IL-2 also stimulates proliferation of...
Keywords: IL-2 Switch-2 (monomeric):Fc Knobs-into-Holes (human) (rec.), Interleukin-2, T Cell Growth Factor, TCGF, IL-2 pH...
Application: Bioassays
Expressed in: Human cells
Origin: human, mouse
MW: 45+28 kD
From 429.00€ *
Review
FasL (human) (multimeric) (rec.)
FasL (human) (multimeric) (rec.)

Item number: AG-40B-0130-3010

(3 x 10 µg). Human FasL (aa 139-281) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG(R)-tag. Lyophilized. Contains PBS. MultimericFasL (human) is a high activity construct in which two trimeric FasL are artificially linked via the collagen domain of ACRP30. This construct very effectively...
Keywords: MegaFasL, Soluble (human) (rec.), SPA, APL, FasL, APTL, CD178, FASLG, sFasL, CD95-L, APT1LG1, FasL ICD, Fas ligand, CD95...
Application: FasL aggregation stimulator
Expressed in: Human cells
Origin: human, mouse
MW: 40 kD
From 363.00€ *
Review