CD40 (human):Fc (human) (rec)

CD40 (human):Fc (human) (rec)
%
Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
AG-40B-0083-C050 50 µg -

3 - 9 business days*

10 %
286.00€
257.40€
AG-40B-0083-3050 150 µg (3 x 50 µg) -

3 - 9 business days*

10 %
572.00€
514.80€
 
(3 x 50µg). The Fc portion of human IgG1 is fused to the C-terminus of human CD40 (amino acids... more
Product information "CD40 (human):Fc (human) (rec)"
(3 x 50µg). The Fc portion of human IgG1 is fused to the C-terminus of human CD40 (amino acids 21-193). Lyophilized. Contains PBS. Binds human and mouse CD40. CD40 belongs to the TNF-receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. The interaction of CD40-CD40L is necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells and macrophages. Consistent with its widespread expression on normal cells, CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.
Keywords: Tumor Necrosis Factor Receptor Superfamily Member 5, TNFRSF5, CD40L Receptor
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-40B-0083

Properties

Application: Bioassays
Conjugate: No
Host: Human cells
Species reactivity: human, mouse
MW: 54 kD
Format: Lyophilized

Database Information

KEGG ID : K03160 | Matching products
UniProt ID : P25942 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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