CD154 -muCD8 Fusion Protein, (human), preservative free

CD154 -muCD8 Fusion Protein, (human), preservative free
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ANC-505-820 25 µg -

3 - 9 business days*

609.00€
 
Human CD154 (CD40 ligand) is a member of the TNF family and is expressed on the surface of... more
Product information "CD154 -muCD8 Fusion Protein, (human), preservative free"
Human CD154 (CD40 ligand) is a member of the TNF family and is expressed on the surface of activated T cells. It can undergo proteolytic cleavage into a 19kDa immunologically active soluble form. Interaction of CD154 and CD40 is essential for isotype switching in B cells. Known genetic defects that alter this interaction lead to impaired immune system function. Increased levels of CD154 has been associated with autoimmune disorders including SLE, CLL and eosinophilic fasciitis. CD154 has been reported to be expressed on vascular endothelial cells, smooth muscle cells, macrophages and activated platelets indicating a role for the CD40-CD154 immunoregulatory signaling in artherosclerosis and cardiovascular disorders.
Keywords: TRAP, CD40L, CD154, CD40LG, CD40-L, CD40 ligand, T-cell antigen Gp39, CD40 ligand, soluble form, CD40 ligand, membrane form, TNF-related activation protein, Tumor necrosis factor ligand superfamily member 5
Supplier: Ancell
Supplier-Nr: 505-820

Properties

Application: FC, ELISA, WB
Conjugate: No
Host: Hamster cells
Species reactivity: porcine
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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