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CD152 [CTLA-4] (human):Fc (human) (rec.) (non-lytic)

Item number: CHI-HF-220A4-C100

The extracellular domain of human CD152 [CTLA-4] (aa 37-160) is fused to the N-terminus of the Fc region of a mutant human IgG1. CD152 (CTLA-4) and CD28, together with their ligands B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD152 and CD28 are...

Keywords:	CTLA4, CD152, CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
Application:	Inhibitor of IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells
Expressed in:	Hamster cells
Origin:	human

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