- Search results for Cay13381-10
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2 products were found matching "Cay13381-10"!
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Item number: Cay11338-1
K252a is a staurosporine analog isolated from Nocardiopsis sp. soil fungi that inhibits protein kinase (PK) C, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphorylase kinase with IC50 values of 470, 140, 270, and 1.7 nM, respectively. Because it inhibits neurotrophin receptor tyrosine kinases, K252a at...
Keywords: | SF 2370,... |
Application: | Kinase inhibitor |
CAS | 99533-80-9 |
MW: | 467.5 D |
From 77.00€
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Item number: Cay13381-1
5-Lipoxygenase (5-LO) initiates the synthesis of leukotrienes (LTs) from arachidonic acid, primarily in certain leukocyte populations. CAY10606 is a potent, reversible inhibitor of 5-LO, both in cell-free assays (IC50 = 86 nM) and in intact neutrophils (IC50 = 230 nM). It prevents the production of LTs in whole...
Keywords: | 2-[(3-chlorophenyl)methyl]-5-hydroxy-1H-benz[g]indole-3-carboxylic acid, ethyl ester |
Application: | 5-LO inhibitor |
CAS | 1159576-98-3 |
MW: | 379.8 D |
From 84.00€
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