5 products were found matching "Cay10010740"!
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CAY10550
Item number: Cay10010740-10
Cellular prion protein (PrPc) is a cell surface glycoprotein expressed in brain, spinal cord, and several peripheral tissues that if mutated to the protease-resistant isoform PrPSc (scrapie PrP, PrPres) can result in one of several fatal neurodegenerative diseases. Prion diseases, including mad cow disease (bovine...
| Keywords: | 3-(4-Nitrophenyl)-1-phenyl-2-pyrazolin-5-one, 2,4-dihydro-5-(4-nitrophenyl)-2-phenyl-3H-pyrazol-3-one |
| Application: | PrPc accumulation inhibitor |
| CAS | 34320-83-7 |
| MW: | 281.3 D |
From 38.00€
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Capsaicin (technical grade)
Item number: Cay10010743-10
Capsaicin is a terpene alkaloid that has been found in Capsicum and has diverse biological activities. It induces inward currents in HEK293 cells expressing rat transient receptor potential vanilloid 1 (TRPV1, EC50 = 0.64 µM at neutral pH), an effect that can be blocked by the TRPV1 inhibitor A-425619. Capsaicin (10...
| Keywords: | N-[(4-hydroxy-3-methoxyphenyl)methyl]-6E-8-methyl-nonenamide |
| Application: | Metabolic studies |
| CAS | 404-86-4 |
| MW: | 305.4 D |
From 43.00€
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PIK-90
Item number: Cay10010749-10
PIK-90 is a potent and cell permeable phosphoinositide 3-kinase (PI3K) inhibitor (IC50 = 11, 350, 18, and 58 nM for p110 subunit isoforms alpha, beta, gamma, and delta, respectively). Through this action, PIK-90 reduces chemotaxis and induces apoptosis in chronic lymphocytic leukemia B cells. It also blocks...
| Keywords: | PIK-85, N-(2,3-dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide |
| Application: | PI3K inhibitor |
| CAS | 677338-12-4 |
| MW: | 351.4 D |
From 26.00€
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17-phenoxy trinor Prostaglandin F2alpha ethyl amide
Item number: Cay10010742-10
Prostaglandin F2alpha (PGF2alpha), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. Both 17-phenyl trinor PGF2alpha and 16-phenoxy tetranor PGF2alpha are metabolically stable analogs of PGF2alpha and potent agonists for the FP receptor. 17-phenoxy trinor...
| Keywords: | 17-phenoxy trinor PGF2alpha ethyl amide,... |
| Application: | Bioactive Lipid Assays |
| CAS | 1421369-12-1 |
| MW: | 431.6 D |
From 117.00€
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SC-51322
Item number: Cay10010744-10
The prostaglandin E2 (PGE2) receptor (EP1) is involved in triggering PGE2-mediated pain as well as neuronal survival and growth. SC-51322 is a selective EP1 antagonist that inhibits PGE2 signaling in a guinea pig ileum muscle strip assay with a pA2 value of 8.1 and demonstrates analgesic activity in a mouse writhing...
| Keywords: | 8-chloro-2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]hydrazide, dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid |
| Application: | EP1 antagonist |
| CAS | 146032-79-3 |
| MW: | 457.9 D |
From 27.00€
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