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CAY10416
CAY10416

Item number: Cay70635-5

Dual cyclooxygenase-2 (COX-2)/5-lipoxygenase (5-LO) inhibitors are potential therapeutic agents for inflammatory diseases and for prostate cancer. CAY10416 is a dual COX-2/5-LO inhibitor with IC50 values of 50 and 3 nM, respectively. The selectivity of CAY10416 for COX is greater than 200-fold for COX-2 versus...
Keywords: 3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole
Application: COX-2 inhibitor, 5-LO inhibitor
CAS 443919-96-8
MW: 536.6 D
From 77.00€ *
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Asterric Acid
Asterric Acid

Item number: Cay70630-5

Asterric acid is an antibiotic fungal metabolite that completely inhibits the binding of the potent vasoconstrictor endothelin (ET)-1 to the ETA receptor in A10 cells at 0.1 µM. Asterric acid derivatives have also been shown to inhibit VEGF-induced tube formation of human umbilical vein endothelial cells at 3-10 µM,...
Keywords: Dimethylosoic Acid, RES-1214-1, TAN 1415A, 2-(2-carboxy-3-hydroxy-5-methylphenoxy)-5-hydroxy-3-methoxy-benzoic acid,...
Application: Endothelin receptor type A antagonist
CAS 577-64-0
MW: 348.3 D
From 287.00€ *
Review