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SU 9516
Item number: Cay14796-1
SU 9516 is a 3-substituted indolinone that has anti-proliferative and pro-apoptotic activity in tumor cells. It is a potent inhibitor of several cyclin-dependent kinases (CDKs) with selectivity for Cdk2 (IC50s = 22, 40, and 200 nM for Cdk2/cyclin A, Cdk1/cyclin B, and Cdk4/cyclin D1). It does not inhibit PKC, p38,...
| Keywords: | 1,3-dihydro-3Z-(1H-imidazol-5-ylmethylene)-5-methoxy-2H-indol-2-one |
| Application: | CDK inhibitor |
| CAS | 377090-84-1 |
| MW: | 241.3 D |
From 43.00€
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ICI 216140
Item number: Cay17479-5
Bombesin is a peptide, originally isolated from the skin of the European fire-bellied toad, with pressor and sympathoexcitatory activity. Its three receptors are distributed throughout the central and peripheral nervous system and are involved in gastric acid secretion, emotional response, temperature control,...
| Keywords: | N-(2-methyl-1-oxopropyl)-7-D-alanine-9-(N-methyl-L-leucinamide)-3-9-neuromedin C |
| Application: | GRP/bombesin receptor 2 antagonist |
| CAS | 124001-41-8 |
| MW: | 916.1 D |
From 205.00€
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