- Search results for Cay15577
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4 products were found matching "Cay15577"!
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Item number: Cay15577-1
The P2X purinergic receptors are ligand-gated ion channels that are activated by extracellular ATP. BzATP (ammonium salt) is an activator of the P2X receptors that exhibits 5-30-fold greater potency at the P2X7 receptor than ATP. It activates the human, rat, and mouse receptors with EC50 values of 0.7, 3.6, and 285...
Keywords: | (2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(((hydroxy((hydroxy(phosphonooxy)phosphoryl)oxy)phosphoryl)oxy)methyl)... |
Application: | P2X receptor activator |
MW: | 816.6 D |
60.00€
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Item number: Cay15557-1
Ramiprilat is the active metabolite of ramipril (Cay-15558) and functions as an angiotensin-converting enzyme inhibitor (pKi = 9.08 in human heart) to suppress the conversion of angiotensin I to angiotensin II and the degradation of bradykinin, thereby preventing vasoconstriction. Furthermore, ramiprilat is reported...
Keywords: | Ramipril Diacid,... |
Application: | ACE inhibitor |
CAS | 87269-97-4 |
MW: | 388.5 D |
From 84.00€
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Item number: Cay11577-5
Zaleplon (Cay-11577) is an analytical reference material that is functionally categorized as a sedative. It is a pyrazolopyrimidine that selectively activates the GABAA alpha1 receptor subunit (EC50 = 1.1 µM), producing a sedative effect. It is characterized as being an ultra-short-acting sedative due to short Tmax...
Keywords: | CL 284,846, N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-N-ethyl-acetamide |
Application: | Analytical reference material, Sedative, GABAA alpha1 receptor subunit activator |
CAS | 151319-34-5 |
MW: | 305.3 D |
From 109.00€
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Item number: Cay15777-100
Metaxalone is a skeletal muscle relaxant. It inhibits the proliferation of, and induces apoptosis in, RAW 264.7 cells in vitro when used at concentrations ranging from 1 to 100 µM. Metaxalone also reduces LPS-induced increases in COX-1, COX-2, and NF-kB levels and inhibits LPS-induced production of TNF-alpha, IL-6,...
Keywords: | AHR 438, NSC 170959, 5-[(3,5-dimethylphenoxy)methyl]-2-oxazolidinone |
Application: | Skeletal muscle relaxant |
CAS | 1665-48-1 |
MW: | 221.3 D |
From 84.00€
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