- Search results for Cay15371
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11 products were found matching "Cay15371"!
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Item number: Cay15371-5
Butein is a plant polyphenol that is classified as a chalcone, due to the propenone linkage between the phenol groups. Like other polyphenols, butein is a potent antioxidant and affects the numerous pathways modulated by oxidant tone, including inflammation, cancer, and immune response. It inhibits 5-lipoxygenase,...
Keywords: | 2',3,4,4'-tetrahydroxy Chalcone, (2E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one |
Application: | Potent antioxidant, 5-lipoxygenase inhibitor |
CAS | 487-52-5 |
MW: | 272.3 D |
From 43.00€
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Item number: Cay15377-1
Venturicidin A is a macrolide antibiotic isolated from strains of Streptomyces. It is active against fungi in the genus Venturia which cause apple scab, as well as other fungi, but not against higher plants. Venturicidin A is also cytotoxic against trypanosomes (IC50 = 120-540 ng/ml) while being more than 25,000...
Keywords: | Aabomycin A1,... |
Application: | Macrolide antibiotic |
CAS | 33538-71-5 |
MW: | 750 D |
From 168.00€
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Item number: Cay15337-1
Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling. The three human PKD isoforms target a variety of proteins to alter cell proliferation, survival, invasion, and protein transport. CRT0066101 is an inhibitor of all three PKD isoforms...
Keywords: | 2-[4-[[(2R)-2-aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)-phenol, trihydrochloride |
Application: | PKD inhibitor |
CAS | 1781742-22-0 |
MW: | 447.8 D |
From 46.00€
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Item number: Cay15537-1
XLR11 (Cay-11565) is a synthetic cannabinoid (CB) featuring a tetramethylcyclopropyl group, which reportedly confers selectivity for the peripheral CB2 receptor over the central CB1 receptor. It also features an N-(5-fluoropentyl) chain, which increases binding to both CB receptors. FUB-144 is a derivative of XLR11...
Keywords: | FUB-UR-144, [1-[(4-fluorophenyl)methyl]-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-methanone |
Application: | Analytical reference standard, synthetic cannabinoid XLR11 derivative |
CAS | 2185863-15-2 |
MW: | 349.5 D |
From 291.00€
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Item number: Cay11537-1
Thioredoxin 1 (Trx1) is a thiol-disulfide oxidoreductase and part of the antioxidant thioredoxin system that is involved in the maintenance of cellular thiol redox homeostasis. It is ubiquitously expressed, localizes primarily to the cytoplasm with some nuclear localization, and is upregulated in and released from...
Keywords: | Trx1, TrxA |
Application: | FA (Inhibitory) |
Host: | Sheep |
506.00€
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Item number: Cay15379-1
Complex I, also known as NADH:ubiquinone oxidoreductase or NADH dehydrogenase (ubiquinone), catalyzes the transfer of electrons from NADH to ubiquinone (also known as coenzyme Q10) as part of the respiratory chain leading to ATP generation. Piericidin A is an irreversible inhibitor of mitochondrial complex I that...
Keywords: | AR 054, Shaoguanmycin B, SN 198E,... |
Application: | Mitochondrial Complex I inhibitor |
CAS | 2738-64-9 |
MW: | 415.6 D |
From 171.00€
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Item number: Cay15376-1
Roquefortine C is a mycotoxin that was first isolated from a strain of P. roqueforti, a species of Penicillium commercially used to ripen blue-veined cheeses. It has also been isolated from other members of the Penicillium genus found in contaminated food products where it displays neurotoxic properties. It has been...
Keywords: | NSC 292134,... |
Application: | Cytochrome p450 inhibitor |
CAS | 58735-64-1 |
MW: | 389.5 D |
From 229.00€
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Item number: Cay15373-1
Transcriptional activation by NF-kappaB is limited by IkappaBalpha binding, which masks the NF-kappaB nuclear localization signal that initiates nuclear translocation. Cytokines trigger a signaling cascade of kinases that target IkappaBalpha for degradation, enabling NF-kappaB to promote gene expression. Because...
Keywords: | 6-(phenylsulfinyl)-tetrazolo[1,5-b]pyridazine |
Application: | IkappaBalpha ubiquitination inhibitor |
CAS | 62645-28-7 |
MW: | 245.3 D |
From 66.00€
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Item number: Cay15370-1
8-iso Prostaglandin F1beta (8-iso PGF1beta) is an isoprostane. It is a potential autooxidation product of the omega-6 fatty acid dihomo-gamma-linolenic acid (DGLA, Cay-90230). 8-iso PGF1beta (10 µM) induces contractions in isolated neonatal porcine pulmonary arteries.Formal Name:...
Keywords: | 8-epi-9beta-PGF1alpha, 8-iso PGF1beta, 9beta,11alpha,15S-trihydroxy-(8beta)-prost-13E-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 26771-95-9 |
MW: | 356.5 D |
From 117.00€
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Item number: Cay15372-1
Ebastine is a histamine H1 receptor antagonist and prodrug form of carebastine (Cay-23076). Ebastine binds to histamine H1 receptors with an IC50 value of 45 nM. It is selective for histamine H1 receptors over alpha1-adrenergic and muscarinic M1 and M2 receptors (IC50s = 183, 1,100, and >10,000 nM, respectively), as...
Keywords: | LAS-W 090, RP 64305, 1-[4-(1,1-dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-1-butanone |
Application: | Histamine receptor H1 antagonis |
CAS | 90729-43-4 |
MW: | 469.7 D |
From 82.00€
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Item number: Cay15327-1
Vancomycin is a glycopeptide antibiotic identified for its utility in the treatment of gram-positive bacteria, including penicillin-resistant staphylococci. It acts by binding to bacterial cell wall protein precursors, interfering with continuing protein synthesis. Vancomycin resistance in staphylococcal species has...
Keywords: | Lyphocin, Vancomycin hydrochloride |
Application: | Antibiotic |
CAS | 1404-93-9 |
MW: | 1449.3 D |
From 77.00€
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