The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase (Lutcke et al., 1993 [PubMed 8486736]).[supplied by OMIM, Oct 2009], Protein function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from...

Coelenterazine hcp is a synthetic derivative of coelenterazine. The luminescence intensity of its aequorin complex is 190 times higher than that of the aequorin complex formed from native coelenterazine while the response time to calcium is faster. Yellow solid soluble in MeOH or EtOHStore at -20°C and protect from...

Ran is a member of the Ras-superfamily GTPases. Ran is invovled in control of DNA synthesis and of cell cycle progression, and the transport of proteins across the nuclear envelope, as well as in microtubule organization during mitosis.

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

AL 8810 (Cay-16735) is an 11beta-fluoro analog of prostaglandin F2alpha (Cay-16010) which acts as a potent and selective antagonist at the FP receptor. AL 8810 isopropyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular prostaglandin compounds such as...