10 products were found matching "Cay11731"!

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Bosentan
Bosentan

Item number: Cay11731-10

Bosentan is an antagonist of the endothelin receptors type A (Ki = 6.5 nM) and type B (Ki = 340 nM).Formal Name: 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide. CAS Number: 147536-97-8. Synonyms: Ro 47-0203. Molecular Formula: C27H29N5O6S. Formula Weight:...
Keywords: Ro 47-0203, 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide
Application: Endothelin receptor antagonist
CAS 147536-97-8
MW: 551.6 D
From 44.00€ *
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UR-144 N-pentanoic acid metabolite
UR-144 N-pentanoic acid metabolite

Item number: Cay11773-1

UR-144 (Cay-11502) is a potent synthetic cannabinoid (CB) which preferentially binds the peripheral CB2 receptor (Ki = 1.8 nM) over the central CB1 receptor (Ki = 150 nM). UR-144 N-pentanoic acid metabolite is an expected phase I metabolite of UR-144, based on the metabolism of similar cannabimimetics. This...
Keywords: XLR11 N-pentanoic acid metabolite, 3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]-1H-indole-1-pentanoic acid
Application: Analytical reference standard, Expected phase I UR-144 metabolite
CAS 1451369-33-7
MW: 341.5 D
From 158.00€ *
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STF-31
STF-31

Item number: Cay11173-1

Glucose transporter 1 (Glut1) is an inducible carrier of pentoses and hexoses, including glucose. STF-31 is an inhibitor of Glut1 (IC50 = ~1 µM) that blocks glucose uptake. It induces necrosis in cancer cells that lack the von Hippel-Lindau tumor suppressor gene, which overexpress Glut1. Although STF-31 binds Glut1,...
Keywords: 4-[[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinyl-benzamide
Application: GLUT1 inhibitor
CAS 724741-75-7
MW: 423.5 D
From 60.00€ *
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Atazanavir
Atazanavir

Item number: Cay11733-1

Atazanavir is an azapeptide inhibitor of HIV-1 protease (Ki = 2.66 nM). It has antiviral activity against a variety of HIV-1 strains in several cell types with EC50 values ranging from 2.62 to 5.28 nM. Atazanavir exhibits a minor synergistic effect when used in combination with the reverse transcriptase inhibitor...
Keywords: BMS 232632, CGP 73547,...
Application: HIV-1 protease inhibitor
CAS 198904-31-3
MW: 704.9 D
From 49.00€ *
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Temoporfin
Temoporfin

Item number: Cay17333-1

Temoporfin is a synthetic chlorin with light-activated actions. When administered systemically, temoporfin accumulates in tumor cells. When stimulated with light (650-652 nm) in the presence of oxygen, reactive oxygen species are generated, leading to necrosis within the tumor. Different approaches to using...
Keywords: m-THPC, Foscan, KW 2345, 3,3',3'',3'''-(7,8-dihydro-21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-phenol
Application: Light-activated necrosis inducer
CAS 122341-38-2
MW: 680.8 D
From 43.00€ *
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Quinacrine analog 34
Quinacrine analog 34

Item number: Cay17733-1

Quinacrine analog 34 is an inhibitor of autophagy with a minimum effective concentration (MEC) of 0.5 µM in U2OS cells. It induces lysosomal deacidification and accumulation of LC3-II in the same cells when used at concentrations of 0.5 or 3 µM.Formal Name:...
Keywords: 6-chloro-1,2,3,4-tetrahydro-N-[2-(4-methyl-1-piperazinyl)ethyl]-9-acridinamine
Application: Autophagy inhibitor
CAS 1411646-44-0
MW: 358.9 D
From 84.00€ *
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5,7-dichloro Tryptamine (hydrochloride)
5,7-dichloro Tryptamine (hydrochloride)

Item number: Cay17331-5

5,7-dichloro Tryptamine is a ring-substituted tryptamine derivative. Although the biological effects of this compound have not been reported, tryptamines substituted with fluorine at the 5-, 6-, or 7-position have been shown to have 5-HT2C receptor selectivity over both the 5-HT2A and 5-HT2B subtypes. This product...
Keywords: 5,7-dichloro-1H-indole-3-ethanamine, monohydrochloride
Application: Analytical reference standard, Ring-substituted tryptamine derivative
CAS 94850-28-9
MW: 265.6 D
From 60.00€ *
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LY320135
LY320135

Item number: Cay11738-1

LY320135 is a selective cannabinoid (CB) receptor 1 antagonist (Kis = 224 and >10,000 nM for CB1 and CB2, respectively, in vitro). It is selective for CB1 over alpha1- and alpha2- adrenergic, D1 and D2 dopamine, benzodiazepine, histamine H1, GABA, serotonin (5-HT), and muscarinic receptors. It reverses the...
Keywords: 4-[[6-methoxy-2-(4-methoxyphenyl)-3-benzofuranyl]carbonyl]-benzonitrile
Application: Cannabinoid receptor 1 (CB1) antagonist
CAS 176977-56-3
MW: 383.4 D
From 39.00€ *
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Coumestrol
Coumestrol

Item number: Cay11730-1

Coumestrol is a phytoestrogen that occurs naturally in soybeans, spinach, and clover. It competitively (vs. 17beta-estradiol, Cay-10006315) binds the estrogen receptors ERalpha (IC50 = 11 nM) and ERbeta (IC50 = 2 nM) and can induce ER-dependent gene expression in isolated cells. Coumestrol is also a weak antagonist...
Keywords: NSC 22842, 3,9-dihydroxy-6H-benzofuro[3,2-c][1]benzopyran-6-one
Application: Pregnane X receptor antagonist
CAS 479-13-0
MW: 268.2 D
From 60.00€ *
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Makisterone A
Makisterone A

Item number: Cay11739-1

Makisterone A is an ecdysteroid that drives molting in insects. It binds the heterodimeric ecdysone receptor with nanomolar affinity.Formal Name: (2beta,3beta,5beta,22R,24R)-2,3,14,20,22,25-hexahydroxy-ergost-7-en-6-one. CAS Number: 20137-14-8. Molecular Formula: C28H46O7. Formula Weight: 494.7. Purity: >95%....
Keywords: (2beta,3beta,5beta,22R,24R)-2,3,14,20,22,25-hexahydroxy-ergost-7-en-6-one
Application: Ecdysone receptor agonist
CAS 20137-14-8
MW: 494.7 D
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