9 products were found matching "Cay16480"!

Blonanserin is a 4-phenyl-2-(1-piperazinyl) pyridine that acts as an antagonist at dopamine D2, D3, and serotonin 5-HT2A receptors (Kis = 0.14, 0.49, and 0.81 nM, respectively). It binds to 5-HT6 with a Ki value of 11.7 nM and demonstrates relatively low affinity for 5-HT2C (Ki = 26.4 nM), adrenergic alpha1 (Ki =...

Nepsilon-(1-Carboxymethyl)-L-lysine (CML) is an advanced glycation end product (AGE), produced by the oxidative modification of glycated proteins during oxidative stress. Levels of CML increase with aging and during diabetes, cancer, vascular disease, and other pathologies marked by oxidative stress. CML activates...

Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It is active against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s = 0.015-2.0 mg/l)....

Epothilone A (Epo A) is a biologically active macrolide produced from the fermentation of the soil bacteria S. cellulosum that was discovered as a potent antimicrotubule agent. In competition assays, epo A binds to beta-tubulin with a similar order of magnitude as the binding of paclitaxel (Cay-10461) to...

1,2,3-Triheptadecanoyl glycerol is a triacylglycerol that contains heptadecanoic acid (Cay-19722) at the sn-1, sn-2, and sn-3 positions.Formal Name: heptadecanoic acid, 1,1',1''-(1,2,3-propanetriyl) ester. CAS Number: 2438-40-6. Synonyms: Glycerol Triheptadecanoate, TG(17:0/17:0/17:0). Molecular Formula: C54H104O6....

Hemin chloride is an oxidized form of heme that inhibits eukaryotic translation initiation factor 2alpha kinase 1 (eIF2alphaK1), a repressor of eIF-2alpha. This alters the initiation of mRNA translation, evoking a wide array of cellular effects. Hemin chloride is used experimentally to induce the expression of heme...

1,3-Dilinoleoyl glycerol is an unsaturated diacylglycerol with linoleic acid (Cay-90150) (18:2) side-chains attached at both the C-1 and C-3 positions that is useful for lipid research.Formal Name: 9Z,12Z-octadecadienoic acid, 1,1'-(2-hydroxy-1,3-propanediyl) ester. CAS Number: 15818-46-9. Synonyms: 1,3-Dilinolein,...

Zilpaterol is a beta-adrenergic receptor agonist that putatively through activation of protein kinase A increases protein synthesis in skeletal muscle fibers, as well as reduces lipogenesis and increases lipolysis in adipose tissues. It was approved by the FDA in 2006 as a veterinary food additive for the purpose of...

1-thio-beta-D-Glucose is an analog of beta-D-glucose in which sulfur replaces the hydroxyl group at the one position. The thiol group allows diverse chemical reactions, including the thiol-Michael addition reaction and polymerization. 1-thio-beta-D-Glucose can be labeled with technetium-99m for analytical and...