Bisindolylmaleimide V

Bisindolylmaleimide V
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay13300-1 1 mg -

6 - 10 business days*

86.00€
Cay13300-5 5 mg -

6 - 10 business days*

375.00€
Cay13300-10 10 mg -

6 - 10 business days*

666.00€
Cay13300-25 25 mg -

6 - 10 business days*

1,451.00€
 
Bisindolylmaleimide V (BIM V) is a weak inhibitor of protein kinase C (PKC) demonstrating an IC50... more
Product information "Bisindolylmaleimide V"
Bisindolylmaleimide V (BIM V) is a weak inhibitor of protein kinase C (PKC) demonstrating an IC50 value >100 µM. While effectively inactive as a PKC inhibitor, BIM V blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo with an IC50 value of 8 µM.Formal Name: 3,4-di-1H-indol-3-yl-1-methyl-1H-pyrrole-2,5-dione. CAS Number: 113963-68-1. Synonyms: BIM V, Ro 31-6045. Molecular Formula: C21H15N3O2. Formula Weight: 341.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml, DMSO: 20 mg/ml, Ethanol: 20 mg/ml. lambdamax: 278, 375, 471 nm. SMILES: O=C1C(=C(c2c[nH]c3ccccc23)C(=O)N1C)c1c[nH]c2ccccc12. InChi Code: InChI=1S/C21H15N3O2/c1-24-20(25)18(14-10-22-16-8-4-2-6-12(14)16)19(21(24)26)15-11-23-17-9-5-3-7-13(15)17/h2-11,22-23H,1H3. InChi Key: SWAWYMIKGOHZMR-UHFFFAOYSA-N.
Keywords: BIM V, Ro 31-6045, 3,4-di-1H-indol-3-yl-1-methyl-1H-pyrrole-2,5-dione
Supplier: Cayman Chemical
Supplier-Nr: 13300

Properties

Application: S6K inhibitor
MW: 341.4 D
Formula: C21H15N3O2
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 113963-68-1| Matching products
KEGG ID : K04688 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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