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Binimetinib
Binimetinib

Item number: Cay16996-5

Binimetinib is a MEK1 and MEK2 inhibitor (IC50s = 1.8 and 0.92 nM, respectively). It is selective for MEK1/2 over a panel of RAF/MEK/ERK pathway kinases at 10 µM. Binimetinib reduces cell growth in HT-29, COLO 205, and LoVo colorectal cancer cell lines (IC50s = 0.48, 0.52, and 2.2 nM, respectively). It reduces tumor...
Keywords: ARRY-438162, MEK162, 5-[(4-bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide
Application: MEK1/2 inhibitor
CAS 606143-89-9
MW: 441.2 D
From 77.00€ *
Review
MDMB-FUBINACA
MDMB-FUBINACA

Item number: Cay16966-1

AB-FUBINACA (Cay-14039) is an indazole-based synthetic cannabinoid (CB) with 10-fold greater affinity for the CB1 receptor (Ki = 0.9 nM) than that of JWH 018 (Cay-10900). MDMB-FUBINACA is a derivative of AB-FUBINACA in which the terminal aminocarbonyl moiety is replaced by a methyl ester group and the isobutyl...
Keywords: FUB-MDMB, MDMB-Bz-F, N-[[1-[(4-fluorophenyl)methyl]-1H-indazol-3-yl]carbonyl]-3-methyl-L-valine, methyl ester
Application: Analytical reference material, synthetic cannabinoid analog (AB-FUBINACA derivative)
CAS 1971007-93-8
MW: 397.4 D
From 291.00€ *
Review