Bcl 2, aa1-211, Recombinant, Human (B-cell lymphoma protein 2 alpha, Apoptosis regulator Bcl-2, Bcl-

Bcl 2, aa1-211, Recombinant, Human (B-cell lymphoma protein 2 alpha, Apoptosis regulator Bcl-2, Bcl-
Item number Size Datasheet Manual SDS Delivery time Quantity Price
B0807-02F1.100 100 µg - -

3 - 19 business days*

1,137.00€
 
Bcl-2, also known as B-cell lymphoma protein 2 alpha, is an anti-apoptotic protein located... more
Product information "Bcl 2, aa1-211, Recombinant, Human (B-cell lymphoma protein 2 alpha, Apoptosis regulator Bcl-2, Bcl-"
Bcl-2, also known as B-cell lymphoma protein 2 alpha, is an anti-apoptotic protein located primarily in the outer mitochondrial membrane that blocks the apoptotic death of some cells such as lymphocytes. BCL-2 is thought to regulate cell death by controlling the mitochondrial membrane permeability during apotosis. Bcl-2 exerts its anti-apoptotic function through inhibiting caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). The Bcl-2 gene has been related with a number of cancers, including melanoma, breast, prostate, and lung carcinomas, as well as schizophrenia and autoimmunity. Source: Recombinant protein corresponding to human Bcl2, aa1-211, with C-terminal His-Tag, expressed in E. coli. Molecular Weight: ~27kD, Applications: Suitable for use in the study of apoptosis, screening inhibitors, and selectivity profiling. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 6 months.
Keywords: BCL2
Supplier: United States Biological
Supplier-Nr: B0807-02F1

Properties

Conjugate: No
MW: 27 kD
Purity: 90%
Format: Purified

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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