7 products were found matching "Cay10532-5"!

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Tetratriaconta-16(Z),19(Z),22(Z),25(Z),28(Z),31(Z)-hexaenoic Acid
Tetratriaconta-16(Z),19(Z),22(Z),25(Z),28(Z),31(Z)-hexaen...

Item number: Cay10539-25

Very long chain polyunsaturated fatty acids (VLCPUFAs) are important components of ceramides and sphingomyelin and are present in retina, sperm, and brain. Tetratriaconta-16(Z),19(Z),22(Z),25(Z),28(Z),31(Z)-hexaenoic acid is a C34:6 VLCPUFA whose specific biological actions are largely unknown. This VLCPUFA, along...
Keywords: 16Z,19Z,22Z,25Z,28Z,31Z-tetratriacontahexaenoic acid
Application: Bioactive Lipid Assays
CAS 105528-06-1
MW: 496.8 D
From 125.00€ *
Review
(S)-Bromoenol lactone-d7
(S)-Bromoenol lactone-d7

Item number: Cay10535-500

(S)-Bromoenol lactone-d7 ((S)-BEL-d7) is intended for use as an internal standard for the quantification of (S)-BEL by GC- or LC-MS. The phospholipases are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components. The calcium-independent...
Keywords: (S)-BEL-d7, 6E-(bromoethylene)tetrahydro-3S-(1-naphthalenyl-2,3,4,5,6,7,8-d7)-2H-pyran-2-one
Application: GC/LC standard
MW: 324.2 D
From 50.00€ *
Review
STO-609 (acetate)
STO-609 (acetate)

Item number: Cay15325-5

STO-609 is a calcium/calmodulin-dependent protein kinase kinase (CaMKK) inhibitor (IC50s = 120 and 40 ng/ml for CaMKKalpha and CaMKKbeta, respectively). It is selective for CaMKKs over CaMKI, CaMKII, CaMKIV, MLCK, PKC, PKA, and p42 MAPK (IC50s = > 10,000 ng/ml for all). STO-609 inhibits phosphorylation of CaMKI and...
Keywords: 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid, monoacetate
Application: Cell-permeable CaMKK inhibitor
CAS 1173022-21-3
MW: 374.4 D
From 43.00€ *
Review
PK11195
PK11195

Item number: Cay10525-50

Benzodiazepines bind two types of receptors, the central gamma-aminobutyric acid A receptor and the peripheral translocator protein (TSPO). PK11195 binds the peripheral benzodiazepine receptor, TSPO, with selectivity and high affinity (Ki = 3.1 nM in cerebellum, 4.1 nM in spinal cord). PK11195, which lacks the...
Keywords: RP 52028, 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide
Application: TSPO blocking, TSPO detection
CAS 85532-75-8
MW: 352.9 D
From 109.00€ *
Review
Sirtinol
Sirtinol

Item number: Cay10523-25

Sirtinol is a cell-permeable inhibitor of sirtuin NAD+-dependent deacetylases, inhibiting the yeast sirtuin Sir2p with an IC50 value of 68 µM and the human sirtuins SIRT1 and SIRT2 with IC50 values of 131 and 38 µM, respectively. It does not alter HDAC1 activity. Sirtinol inhibits the growth of cancer cells and...
Keywords: Sir Two Inhibitor Naphthol, 2-[[(2-hydroxy-1-naphthalenyl)methylene]amino]-N-(1-phenylethyl)-benzamide
Application: Sirtuin inhibitor
CAS 410536-97-9
MW: 394.5 D
From 92.00€ *
Review
Anti-Chemokine-Like Receptor 1
Anti-Chemokine-Like Receptor 1

Item number: Cay10325-1

Chemokine-Like Receptor 1 (CMKLR1) is a G protein-coupled receptor relevant to the cellular chemotaxis of dendritic cells and macrophages. This receptor is also expressed in brain, liver, lung, and kidney tissues. Chemerin, or TIG2, has been identified as the natural ligand for this receptor. Resolvin E1 has also...
Keywords: Anti-CMKLR1, Anti-CHEMR23, Anti-Chemokine-like receptor 1, Anti-Chemokine-like receptor 1, Anti-G-protein coupled receptor...
Application: FC, IF, IHC, WB
Host: Rabbit
Species reactivity: human
422.00€ *
Review
CAY10535
CAY10535

Item number: Cay10010396-1

TPalpha and TPbeta are two isoforms of the human TP receptor, the G protein-coupled receptor (GPCR) that mediates the actions of thromboxane A2 (TXA2). Although their distinct physiological functions have not been fully elucidated, TPbeta is believed to be responsible for vascular endothelial growth factor-induced...
Keywords: N-(tert-butylcarbamoyl)-2-(3-methoxyphenoxy)-5-nitrobenzenesulfonamide
Application: TP receptor antagonist
CAS 945716-28-9
MW: 423.4 D
From 48.00€ *
Review