6 products were found matching "Cay10532"!
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Tetratriaconta-16(Z),19(Z),22(Z),25(Z),28(Z),31(Z)-hexaen...
Item number: Cay10539-25
Very long chain polyunsaturated fatty acids (VLCPUFAs) are important components of ceramides and sphingomyelin and are present in retina, sperm, and brain. Tetratriaconta-16(Z),19(Z),22(Z),25(Z),28(Z),31(Z)-hexaenoic acid is a C34:6 VLCPUFA whose specific biological actions are largely unknown. This VLCPUFA, along...
| Keywords: | 16Z,19Z,22Z,25Z,28Z,31Z-tetratriacontahexaenoic acid |
| Application: | Bioactive Lipid Assays |
| CAS | 105528-06-1 |
| MW: | 496.8 D |
From 125.00€
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CAY10597
Item number: Cay10012539-5
The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and CRTH2/DP2. In humans, CRTH2/DP2 is expressed on Th2 cells, eosinophils, and basophils where it mediates the chemotactic activity of PGD2. CAY10597, as a racemic mixture, is...
| Keywords: | 5-chloro-1'-[(2-fluorophenyl)methyl]-2,2',5'-trioxo-spiro[3H-indole-3,3'-pyrrolidine-1(2H)-acetic acid |
| Application: | CRTH2receptor antagonist, DP2 receptor antagonist |
| CAS | 916046-55-4 |
| MW: | 416.8 D |
From 96.00€
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CAY10592
Item number: Cay10012536-5
Peroxisome proliferator-activated receptors (PPARs) alpha, delta, gamma are ligand-activated nuclear transcription factors involved in the regulation of energy homeostasis as well as insulin sensitivity and glucose metabolism. Pharmacologies of PPARdelta receptor agonists, though relatively obscure, have recently...
| Keywords: | 2-[4-[[3,3-bis(4-bromophenyl)-2-propen-1-yl]thio]-2-chlorophenoxy]-acetic acid |
| Application: | PPARdelta agonist |
| CAS | 685139-10-0 |
| MW: | 568.7 D |
From 48.00€
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CAY10595
Item number: Cay10012553-1
The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and CRTH2/DP2. In humans, CRTH2/DP2 is expressed on Th2 cells, eosinophils, and basophils where it mediates the chemotactic activity of PGD2. CAY10595, as a racemic mixture, is...
| Keywords: | 5-chloro-1'-[5-chloro-2-fluorophenyl)methyl]-2,2',5'-trioxo-spiro[3H-indole-3,3'pyrrolidine]-1(2H)-acetic acid |
| Application: | CRTH2receptor antagonist, DP2 receptor antagonist |
| CAS | 916047-16-0 |
| MW: | 451.2 D |
From 89.00€
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Sirtinol
Item number: Cay10523-5
Sirtinol is a cell-permeable inhibitor of sirtuin NAD+-dependent deacetylases, inhibiting the yeast sirtuin Sir2p with an IC50 value of 68 µM and the human sirtuins SIRT1 and SIRT2 with IC50 values of 131 and 38 µM, respectively. It does not alter HDAC1 activity. Sirtinol inhibits the growth of cancer cells and...
| Keywords: | Sir Two Inhibitor Naphthol, 2-[[(2-hydroxy-1-naphthalenyl)methylene]amino]-N-(1-phenylethyl)-benzamide |
| Application: | Sirtuin inhibitor |
| CAS | 410536-97-9 |
| MW: | 394.5 D |
From 92.00€
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Doxifluridine
Item number: Cay10253-1
Doxifluridine is an intermediary prodrug of fluorouracil (Cay-14416), the pyrimidine analog that inhibits thymidylate synthase selectively in tumor cells, interfering with DNA synthesis. Doxifluridine is one of two intermediary metabolites formed during metabolic conversion of the chemotherapeutic prodrug,...
| Keywords: | 5-DFUR, Ro 21-9738, 5'-deoxy-5-fluoro-uridine |
| Application: | Intermediary metabolite of Capecitabine |
| CAS | 3094-09-5 |
| MW: | 246.2 D |
From 84.00€
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