BX-795

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Item number	Size	Manual	Delivery time	Price
SYN-1026-M001	1 mg	-	3 - 9 business days*	100.00€
SYN-1026-M005	5 mg	-	3 - 9 business days*	132.00€
SYN-1026-M010	10 mg	-	3 - 9 business days*	178.00€
SYN-1026-M050	50 mg	-	3 - 9 business days*	711.00€
SYN-1026-M100	100 mg	-	3 - 9 business days*	-

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Soluble in DMSO or ethanol. BX795 was initially developed as a PDK1 inhibitor (direct competitive... more

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Product information "BX-795"

Soluble in DMSO or ethanol. BX795 was initially developed as a PDK1 inhibitor (direct competitive inhibitor IC(50) 11nM for PDK1) and has been shown to be a potent and relatively specific inhibitor of TBK1 and IKK-epsilon. It blocks the phosphorylation, nuclear translocation, and transcriptional activity of interferon regulatory factor 3. BX795 also is a potent inhibitor of cell growth of multiple cancer cell lines with IC(50) values ranging from submicromolar amounts (0.368µM to greater than 450µM. Target: PDK1 , Kinase Group: AGC , Substrate: Serine-Threonine

Keywords:	BX795
Supplier:	SYNkinase
Supplier-Nr:	1026

Properties

Application:	PDPK1 inhibitor
MW:	591,5 D
Formula:	C23H26IN7O2S
Purity:	>95%
Format:	Solid

Database Information

CAS :	702675-74-9\| Matching products
KEGG ID :	K06276 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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