- Search results for Cay11284
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11 products were found matching "Cay11284"!
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Item number: Cay11428-5
4-deoxy Nivalenol is a trichothecene mycotoxin that has been found in Fusarium. It binds to eukaryotic ribosomes and inhibits protein synthesis in mice when administered at doses ranging from 5 to 25 mg/kg. 4-deoxy Nivalenol (0.1 and 0.2 mg/kg) induces emesis in pigs and decreases feed consumption in pigs when...
Keywords: | Deoxynivalenol, DON, NSC 269144, Vomitoxin, 12,13-epoxy-3alpha,7alpha,15-trihydroxy-trichothec-9-en-8-one |
Application: | Type B trichothecene mycotoxin, Protein biosynthesis inhibitor |
CAS | 51481-10-8 |
MW: | 296.3 D |
From 66.00€
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Item number: Cay11248-1
Mouse anti-DYKDDDDK IgG (Clone M2) conjugated to DyLight(R) 488 Antibody: Mouse monoclonal anti-DYDDDDK IgG Clone: M2 Isotype: IgG Dye: DyLight(R) 488 Excitation max. lambda: 493 nm Emission max. lambda: 518 nm Uses: Fluorescence-activated cell sorting, flow cytometry, and protein microarraysEmission: 518 nm....
Application: | IF |
Host: | Mouse |
488.00€
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Item number: Cay18124-1
Lysine-specific demethylase 1 (LSD1) belongs to the family of flavin adenine dinucleotide (FAD)-dependent amine oxidases that include monoamine oxidases (MAOs). RN-1 is a potent, irreversible inhibitor of LSD1 (IC50 = 70 nM). It is much less effective against MAO-A and MAO-B (IC50s = 0.51 and 2.8 µM, respectively)....
Keywords: | LSD1 Inhibitor IV, rel-1-(4-methyl-1-piperazinyl)-2-[[(1R,2S)-2-[4-(phenylmethoxy)phenyl]cyclopropyl]amino]-ethanone,... |
Application: | Irreversible LSD1 inhibitor |
CAS | 1781835-13-9 |
MW: | 452.4 D |
From 77.00€
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Item number: Cay21184-1
Chk2 inhibitor is an inhibitor of checkpoint kinase 2 (Chk2, IC50 = 13.5 nM). It is selective for Chk2 over Chk1 (IC50 = 220.4 nM). It inhibits Chk2 autophosphorylation at the serine in position 516 in non-cancerous 184B5 cells that contain wild-type p53 and in MDA-MB-231 cells that contain mutated p53 when used at...
Keywords: | SC-203885, (5Z)-5-(2-amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-3,4,5,10-tetrahydro-azepino[3,4-b]indol-1(2H)-one |
Application: | CHEK2 inhibitor |
CAS | 724708-21-8 |
MW: | 295.3 D |
From 324.00€
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Item number: Cay11824-5
Bacoside A3 is a triterpenoid saponin first isolated from B. monniera. Bacoside A3 inhibits the ATP-binding cassette transporter P-glycoprotein (P-gp), decreasing efflux 4-fold compared with control in vitro. An extract containing bacoside A3 and bacopaside II (4 and 1.3 µg/mg extract, respectively) administered for...
Keywords: | Bacopa Pgp, (3beta,16beta,23R)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-3-yl... |
Application: | P-glycoprotein inhibitor |
CAS | 157408-08-7 |
MW: | 929.1 D |
774.00€
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Item number: Cay18412-10
GDC-0068 is a selective, ATP-competitive, pan-Akt inhibitor that targets Akt1, 2, and 3 with IC50 values of 5, 18, and 8 nM, respectively in cell-free assays. It is 620-fold selective for Akt over protein kinase A and has been shown to block Akt signaling selectively in cultured tumor cell lines characterized by...
Keywords: | Ipatasertib, RG-7440,... |
Application: | Akt (protein kinase B) inhibitor |
CAS | 1001264-89-6 |
MW: | 458 D |
From 77.00€
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Item number: Cay11842-10
10-Gingerol is a phenol that has been found in Z. officinale and has diverse biological activities. It scavenges DPPH (Cay-14805), superoxide, and hydroxyl radicals in cell-free assays (IC50s = 10.47, 1.68, and 1.35 µM, respectively) and inhibits oxidative burst induced by N-formyl-Met-Leu-Phe (fMLP, Cay-21495) in...
Keywords: | 5S-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone |
Application: | Antifungal agent |
CAS | 23513-15-7 |
MW: | 350.5 D |
From 52.00€
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Item number: Cay11184-25
Resolvin D2-d5 (RvD2-d5) is intended for use as an internal standard for the quantification of resolvin D2 (Cay-10007279) by GC- or LC-MS. Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). In addition to being anti-inflammatory, resolvins...
Keywords: | 7(S),16(R),17(S)-Resolvin D2-d5, RvD2-d5, 7S,16R,17S-trihydroxy-4Z,8E,10Z,12E,14E,19Z-21,21',22,22,22-d5 docosahexaenoic acid |
Application: | Standard, bioactive lipid assays |
CAS | 1881277-33-3 |
MW: | 381.5 D |
From 226.00€
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Item number: Cay11684-25
Bakuchiol is a natural meroterpene isolated from P. corylifolia, a plant used in traditional Asian medicine. In addition to having antioxidant and antibacterial actions, bakuchiol has retinol-like effects on gene expression and properties of the skin. Bakuchiol also inhibits DNA polymerase and...
Keywords: | (S)-(+)-Bakuchiol, 4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadien-1-yl]-phenol |
Application: | PTP1B inhibitor |
CAS | 10309-37-2 |
MW: | 256.4 D |
From 72.00€
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Item number: Cay11084-25
UNC0631 is a potent and selective inhibitor of G9a activity in vitro (IC50 = 4 nM) and G9a/GLP-mediated dimethylation of histone 3 on lysine 9 in MDA-MB-231 cells (IC50 = 25 nM). It potently inhibits G9a/GLP activity in a variety of cancer cell lines as well as in the human fetal lung IMR-90 cell line.Formal Name:...
Keywords: | N-[1-(cyclohexylmethyl)-4-piperidinyl]-2-[hexahydro-4-(1-methylethyl)-1H-1,4-diazepin-1-yl]-6-methoxy-7-[3-(1-piperidinyl)... |
Application: | Potent, selective EHMT1 / EHMT2 inhibitor |
CAS | 1320288-19-4 |
MW: | 635.9 D |
From 50.00€
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Item number: Cay14128-5
Fludarabine is an intermediate active metabolite of the prodrug fludarabine phosphate (Cay-14251). It is produced by the dephosphorylation of fludarabine phosphate in vivo and re-phosphorylation intracellularly to 2-fluoro-ara-ATP, another active metabolite. Fludarabine inhibits the proliferation of RPMI-8226,...
Keywords: | F-ara-A, NSC 118218, 9-beta-D-arabinofuranosyl-2-fluoro-9H-purin-6-amine |
Application: | 9-beta-D-arabinofuranosyladenine analog, Metabolic studies |
CAS | 21679-14-1 |
MW: | 285.2 D |
From 43.00€
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